Clinical Trials in Cleveland

Showing 6881-6900 of 15,050 trials

A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease

NCT01559363

The primary objective of this study Phase 1b was to determine the safety, plasma pharmacokinetics, and maximum tolerated dose (MTD) of tesevatinib when administered to participants with autosomal dominant polycystic kidney disease (ADPKD). The primary objective of this study Phase 2a was to evaluate the annualized change in glomerular filtration rate (GFR) in participants with ADPKD when treated with tesevatinib.

Polycystic Kidney, Autosomal Dominant

Kadmon, a Sanofi Company69 participantsStarted Oct 2012

Los Angeles, California, United States • Denver, Colorado, United States • Kansas City, Kansas, United States +8 more locations

TERMINATEDPhase 2< 1 mile

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease

NCT03352557

The primary objective of the placebo-controlled period is to evaluate the safety and tolerability of BIIB092 in participants with mild cognitive impairment (MCI) due to Alzheimer's disease (AD) or with mild AD. The secondary objectives of the placebo-controlled period are to evaluate the efficacy of multiple doses of BIIB092 in slowing cognitive and functional impairment in participants with MCI due to AD or with mild AD, and to evaluate the immunogenicity of BIIB092 after multiple doses in participants with MCI due to AD or with mild AD. The primary objective of the long-term extension period is to evaluate the long-term safety and tolerability of BIIB092 in participants with MCI due to AD or with mild AD.

Alzheimer's Disease

Biogen654 participantsStarted May 2018

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +98 more locations

A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease

Find Trials by Condition in Cleveland

RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial

Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)

Clinical Study to Evaluate Treatment With ORACEA® for Geographic Atrophy (TOGA)

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women

Evaluation of a TAP Block Given During Laparoscopic Colorectal Surgery to Help Control Pain

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

A Phase 2 Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE)

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140

SUPERa Stenting After SUBintimal Crossing of TASC C-D Femoro-popliteal Lesions in CLI Patients

Open-label Study of the Safety and Activity of Oprozomib in Patients With Hematologic Malignancies

A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis

Innovative Methods to Assess Psychotherapy Practices (imAPP)

A Study to Assess Long-term Safety, Tolerability and Efficacy of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Diagnostic Accuracy Of Forced Oscillation Technique To Detect Lung Function Anomalies