Clinical Trials in Cleveland

Showing 6341-6360 of 15,050 trials

Study of BPZE1 Intranasal Pertussis Vaccine (Administered Via VaxINator(TM)), Prime + Boost, in Healthy Adults

NCT03942406

This study evaluates the safety and immunogenicity of the BPZE1 live attenuated pertussis vaccine, intended to prevent nasopharyngeal colonization and pertussis disease, and compares a single (prime) BPZE1 dose or BPZE1 2-dose (prime + boost) to a single (prime) Boostrix or Boostrix prime + BPZE1 boost.

PertussisWhooping Cough

ILiAD Biotechnologies300 participantsStarted Jun 2019

Cleveland, Ohio, United States • Tomball, Texas, United States • West Jordan, Utah, United States

COMPLETEDPhase 2< 1 mile

Down Syndrome Memantine Follow-up Study

NCT02304302

The purpose of this research study is to learn if the medication Memantine Hydrochloride (the study medication) can help adolescents and young adults with Down syndrome. Dr. Alberto Costa and his research team want to see if a 16-week treatment with this medication can improve the participant's ability to learn and remember things. In this study, memantine hydrochloride will be used. Thus, the researchers want to learn whether the study drug can help improve memory in young adults with Down syndrome. To test the effect of the study medicine, half of the people in the study will receive the study medicine and half will receive a placebo (an inactive substance). Memantine is an approved medication to treat memory and thinking problems in persons with Alzheimer disease. However, little is known about the effect of this medication in persons with Down syndrome and it has not been approved for use in persons with Down syndrome.

Down SyndromeIntellectual Disability

University Hospitals Cleveland Medical Center160 participantsStarted Oct 2014

Cleveland, Ohio, United States • São Paulo, São Paulo, Brazil

Study of BPZE1 Intranasal Pertussis Vaccine (Administered Via VaxINator(TM)), Prime + Boost, in Healthy Adults

Down Syndrome Memantine Follow-up Study

Find Trials by Condition in Cleveland

Mesenchymal Stem Cells in Early Rheumatoid Arthritis

The TIME-2b Study: A Study of AKB-9778 (Razuprotafib), a Novel Tie 2 Activator, in Patients With Non-Proliferative Diabetic Retinopathy (NPDR)

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease

Mobile Devices to Detect Early Pneumonitis in Stage III NSCLC Patients on Durvalumab.

Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC

Study of Lenvatinib in Subjects With Advanced Endometrial Cancer and Disease Progression

Clinical Performance of Senofilcon A Investigational Lens

Effect of GTx-758 on Total and Free Testosterone Levels in Men With Prostate Cancer

Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE

A Study of the Burden of Illness and Treatment Patterns in Teenagers and Adults With Hereditary Angioedema

Venous Sinus Stenting With the River Stent in IIH

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

Efficacy and Safety of Increasing Doses of DaxibotulinumtoxinA for Injection (DAXI for Injection) in the Treatment of Moderate or Severe Lateral Canthal Lines

The Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less Than 12 Years of Age

Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial

S1916 Digital Medicine Program for Pain Control in Cancer Patients

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2)

COVID-19 and Anti-CD14 Treatment Trial