Clinical Trials in Cleveland

Showing 4701-4720 of 19,775 trials

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

NCT05030441

This is an open-label, multicenter study exploring the efficacy of ivosidenib in patients with clonal cytopenia of undetermined significance (CCUS) with mutations in IDH1. The purpose is to establish proof of principle that ivosidenib is well-tolerated and potentially efficacious in improving blood count abnormalities in these patients. The study will also be offered in a decentralized, remote structure to patients.

Clonal Cytopenia of Undetermined Significance

Washington University School of Medicine20 participantsStarted Apr 2022

St Louis, Missouri, United States • Cleveland, Ohio, United States

COMPLETEDPhase 3< 1 mile

Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis

NCT05142774

This is an open-label, long-term multicenter, study to evaluate the safety and efficacy of topical tapinarof cream, 1% in subjects with atopic dermatitis. Subjects in this study have completed treatment in one of two Phase 3 pivotal studies (DMVT-505-3101 or DMVT-505-3102) or completed treatment in the DMVT-505-2104 study, or directly enrolled into this study. This study will consist of up to 48 weeks of treatment and a 1 week safety follow-up period.

Atopic Dermatitis

Organon and Co728 participantsStarted Oct 2021

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Scottsdale, Arizona, United States +109 more locations

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis

Find Trials by Condition in Cleveland

Expanded Access of Sotorasib

Nonalcoholic Fatty Liver Disease (NAFLD) Database 3

Older Adult Effectiveness of 2 Treatments

Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis in the Treatment of Abdominal Aortic Aneurysms

COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations

A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours

A Study to Evaluate the Safety and Tolerability of Maximal Use Ruxolitinib Cream

Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery

A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis

Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses

CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

A Real-World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma