Clinical Trials in Cleveland

Showing 3421-3440 of 19,775 trials

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

NCT04722887

The purpose of this study is to evaluate the safety and tolerability of 72 milligrams per kilogram (mg/kg) and 180 mg/kg Alpha-1 15%, administered as a single-dose subcutaneous (SC) infusion and subsequently as weekly SC infusions over 8 weeks in participants with Alpha1-Antitrypsin Deficiency (AATD).

Alpha1-Antitrypsin Deficiency

Grifols Therapeutics LLC17 participantsStarted Aug 2021

Los Angeles, California, United States • Gainesville, Florida, United States • Miami, Florida, United States +2 more locations

Active Not RecruitingPhase 3< 1 mile

A Study of Zigakibart in Adults With IgA Nephropathy

NCT05852938

Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy

IgA NephropathyImmunoglobulin A Nephropathy

Novartis Pharmaceuticals383 participantsStarted Jul 2023

Birmingham, Alabama, United States • Huntsville, Alabama, United States • San Francisco, California, United States +197 more locations

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

A Study of Zigakibart in Adults With IgA Nephropathy

Find Trials by Condition in Cleveland

Sequential or CombinaTion Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

FastWire REvascularisation of Extremities, (For LOWer Limbs) - FREEFLOW

A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

Evaluation of A Clinical Diagnostic Test for CRDS

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence

A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

ASPIRES (Activating Cancer Survivors and Their Primary Care Providers to Increase Colorectal Cancer Screening) Study

A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma

UNITY VCS Vitreoretinal Surgery

Cognitive Control to Boost Physical Activity Adherence