Clinical Trials in Cleveland

Showing 3301-3320 of 19,775 trials

Vascular Lab Resource (VLR) Biorepository

NCT05628948

This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases. The purpose of this initiative is to develop an enduring tool to allow for collaborative research between clinicians at Cleveland Clinic Main Campus and basic scientists at the Lerner Research Institute. This collaboration will allow resources to be available to clinical and basic researchers alike. This tool will enable research of vascular disease in the Vascular Lab and will leverage this valuable asset to the fullest extent to allow for interdepartmental collaboration.

Cardiovascular DiseasesMetabolic DiseasePeripheral Artery Disease+13 more

The Cleveland Clinic500 participantsStarted Nov 2019

Cleveland, Ohio, United States

Active Not RecruitingPhase 2< 1 mile

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

NCT04579380

This trial studies how well tucatinib works for solid tumors that make either more HER2 or a different type of HER2 than usual (HER2 alterations) The solid tumors studied in this trial have either spread to other parts of the body (metastatic) or cannot be removed completely with surgery (unresectable). All participants will get both tucatinib and trastuzumab. People with hormone-receptor positive breast cancer will also get a drug called fulvestrant. The trial will also look at what side effects happen. A side effect is anything a drug does besides treating cancer.

Uterine NeoplasmsUterine Cervical NeoplasmsBiliary Tract Neoplasms+3 more

Seagen, a wholly owned subsidiary of Pfizer217 participantsStarted Jan 2021

Phoenix, Arizona, United States • Tempe, Arizona, United States • Tucson, Arizona, United States +103 more locations

Vascular Lab Resource (VLR) Biorepository

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Find Trials by Condition in Cleveland

Reflex Excitability in Post-stroke Stiff-Knee Gait

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria

Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease

Spine Oncology Registry

A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

C.Difficile Observational Study

Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

Pancreatic Cancer Detection Consortium

Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis

A Multicentre Observational Study to Evaluate Clinical Outcomes of the G7 Acetabular System