Clinical Trials in Cleveland

Showing 3101-3120 of 19,775 trials

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

NCT06777901

The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages. The main question it aims to answer is: Is treatment with Auryon Atherectomy System more effective than angioplasty alone in preventing death, amputation, revascularization and improving patency? Researchers will compare the Auryon Atherectomy System with balloon angioplasty to balloon angioplasty alone.

Peripheral Arterial Diseases

Angiodynamics, Inc.224 participantsStarted Apr 2025

Phoenix, Arizona, United States • San Diego, California, United States • Gray, Louisiana, United States +6 more locations

RECRUITING< 1 mile

Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

NCT05400499

Inability to align and refocus the eyes on the objects at different depths, i.e., vergence impairment, frequently affects the quality of life in patients with Parkinson's disease. Our study aims to understand the location-specific effects of subthalamic region deep brain stimulation on vergence by integrating the patient-specific deep brain stimulation models and high-resolution eye-tracking measures. The knowledge gained will allow us to find the most beneficial stimulation location and parameters for improving binocular coordination and vergence while preserving the ability to treat motor symptoms in Parkinson's disease.

Parkinson's Disease

VA Office of Research and Development40 participantsStarted Oct 2022

Cleveland, Ohio, United States

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

Find Trials by Condition in Cleveland

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery

[18F]PI-2620 Phase 3 Histopathological Study

First-in-Human, Phase I, Open-label, Multicenter, Dose Escalation Clinical Study

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

A Study to Check Liver Health in Boys With XLMTM, a Serious Genetic Muscle Condition

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Adults With Solid Malignancies

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)

Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC