Clinical Trials in Cleveland

Showing 2721-2740 of 19,775 trials

Sternal Plating High Risk

NCT06660186

Participants are being invited to participate in a research study at University Hospitals because they have heart disease and are scheduled for open heart surgery. Currently, UH cardiac surgeons close the sternum (or breastbone) after a sternotomy (procedure that allows a doctor to reach the heart and blood vessels) with either a rigid plate fixation Sternal Plate or a Wire Cerclage. However, the study team would like to further evaluate these two techniques. Any volunteer over the age of 18 who is at an increased risk for developing sternal wound complications may be eligible to participate.

Heart Diseases

University Hospitals Cleveland Medical Center250 participantsStarted Feb 2026

Cleveland, Ohio, United States

Active Not RecruitingNA< 1 mile

Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

NCT05462145

This study will evaluate the safety and effectiveness of the Globe® Pulsed Field System for treating patients with symptomatic paroxysmal or persistent atrial fibrillation (AF).

Paroxysmal Atrial FibrillationPersistent Atrial Fibrillation

Kardium Inc.549 participantsStarted Mar 2023

Birmingham, Alabama, United States • Jonesboro, Arkansas, United States • San Francisco, California, United States +15 more locations

Sternal Plating High Risk

Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

Find Trials by Condition in Cleveland

TVMR With the INNOVALVE System Trial - Early Feasibility Study

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD

Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

A Study of Tiragolumab in Combination With Atezolizumab Compared With Placebo in Combination With Atezolizumab in Patients With Previously Untreated Locally Advanced Unresectable or Metastatic PD-L1-Selected Non-Small Cell Lung Cancer

Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study