Clinical Trials in Cleveland

Showing 2541-2560 of 9,497 trials

Imaging-Guided Vessel Sizing in the Tibial Arteries

NCT04748965

This study aims to investigate the utilization of intravascular imaging in treatment of tibial vessels in peripheral artery disease and critical limb ischemia (CLI). The primary goal is to compare optical coherence tomography (OCT) with traditional digital subtraction angiography (DSA) in determining best treatment strategy and vessel optimization, in an effort to improve long term patency and successful wound healing in CLI. Secondary comparison with intravascular ultrasound (IVUS) is undertaken when clinically feasible. The hypothesis is that the adjunctive use of intravascular imaging will affect vessel sizing and anticipated treatment modalities, and therein affect the long term primary patency rates.

Peripheral Artery DiseaseCritical Limb Ischemia

University Hospitals Cleveland Medical Center40 participantsStarted Aug 2021

Beachwood, Ohio, United States • Cleveland, Ohio, United States • Parma, Ohio, United States

RECRUITINGNA< 1 mile

AltaValve Pivotal Trial

NCT06465745

This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.

Mitral RegurgitationMitral InsufficiencyMitral Valve Incompetence+2 more

4C Medical Technologies, Inc.450 participantsStarted Sep 2024

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +26 more locations

Imaging-Guided Vessel Sizing in the Tibial Arteries

AltaValve Pivotal Trial

Find Trials by Condition in Cleveland

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

Ferric Citrate and Chronic Kidney Disease in Children

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

COVID-19 VaccinE Response in Rheumatology Patients

Promoting Early Intervention Timing and Attention to Language

A Digital Intervention to Improve Physical Activity and Sleep Behaviors in Youth With Psychiatric Diagnoses

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

An Investigation to Validate Speech Perception Assessment for Adult Cochlear Recipients Using a Mobile Research App