Clinical Trials in Cleveland

Showing 1981-2000 of 9,497 trials

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

NCT05209074

This study is a single-arm, phase I trial, up to 16 participants with resectable PDA. The study will examine the efficacy of the mutant IDH1 inhibitor ivosidenib, in conjunction with standard-of-care mFOLFIRINOX in the neoadjuvant setting.

Pancreatic Ductal AdenocarcinomaResectable Pancreatic Cancer

Case Comprehensive Cancer Center16 participantsStarted Sep 2022

Cleveland, Ohio, United States

COMPLETED< 1 mile

Collection of Peripheral Blood From Patients With Hematologic Malignancies With Thrombocytopenia

NCT06824727

The purpose of the research project is to collect one blood sample from participants who are affected by very low platelets as a result of their condition or their treatment.

Thrombocytopenia

Case Comprehensive Cancer Center40 participantsStarted Jan 2025

Cleveland, Ohio, United States

Active Not RecruitingPhase 3< 1 mile

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

NCT05748600

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability of dexpramipexole in participants with eosinophilic asthma.

Eosinophilic AsthmaAsthma; EosinophilicAsthma Attack

Areteia Therapeutics600 participantsStarted Jan 2023

Chandler, Arizona, United States • Peoria, Arizona, United States • Surprise, Arizona, United States +332 more locations

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

Collection of Peripheral Blood From Patients With Hematologic Malignancies With Thrombocytopenia

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

Find Trials by Condition in Cleveland

Strategies and Treatments for Respiratory Infections &Amp; Viral Emergencies (STRIVE): Immune Modulation Strategy Trial

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

CREST-2 Long-term Observational Extension Study

A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC)

A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

A Study in the United Sates That Looks at the Safety and Effectiveness of Pradaxa Pellets in Children Aged 3 Months to Less Than 12 Years Who Need Treatment of a Blood Clot or Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot

A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat

A Clinical Trial to Evaluate the Safety and Immunogenicity of Glycan-trimmed HIV-1 Nanoparticle Vaccine (UVAX-1107), Followed by Homologous or Wild-type HIV-1 Nanoparticle Vaccine (UVAX-1197) Boost, Each Adjuvanted With 3M-052-AF + Alum in Adult Participants Without HIV

Impact of a Health Technology Intervention on Patient Activation in Multiple Myeloma

Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis

A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers

SHAPE for ICP Assessment

A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors

A Multicenter Pragmatic Implementation Study of ECG-AI-Based Clinical Decision Support Software to Identify Low LVEF

Development of Digital Biomarkers in Multiple Sclerosis: Validation Study 2