Clinical Trials in Chicago

Showing 19761-19780 of 20,493 trials

Study of XL999 in Patients With Multiple Myeloma

NCT00304590

This clinical study is being conducted at multiple sites to determine the activity, safety, and tolerability of XL999 when given weekly to patients with relapsed or refractory multiple myeloma. XL999 is a small molecule inhibitor of cellular factors including VEGFR, PDGFR, and FGFR that may be involved in multiple myeloma.

Multiple Myeloma

Symphony Evolution, Inc.4 participantsStarted Feb 2006

Los Angeles, California, United States • Chicago, Illinois, United States • Joliet, Illinois, United States

TERMINATEDPhase 22.2 miles

Study of XL999 in Patients With Previously Treated Ovarian Cancer

NCT00277290

This clinical trial is being conducted at multiple sites to evaluate the activity, safety, and tolerability of XL999 when given weekly to patients with ovarian cancer that has previously been treated with platinum-based chemotherapy. XL999 is a small molecule inhibitor of multiple kinases including VEGFR, PDGFR, FGFR, FLT-3, and Src, which are involved in tumor cell growth, formation of new blood vessels (angiogenesis), and metastasis.

Ovarian Cancer

Symphony Evolution, Inc.24 participantsStarted Jan 2006

Greenbrae, California, United States • Port Saint Lucie, Florida, United States • Chicago, Illinois, United States +6 more locations

Study of XL999 in Patients With Multiple Myeloma

Study of XL999 in Patients With Previously Treated Ovarian Cancer

Find Trials by Condition in Chicago

Randomized Study of Human-Milk Based Nutrition Versus Formula in Premature Infants

Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia

Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis

Normal Pressure Hydrocephalus (NPH) Registry

A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon

A Phase IIIb Study Comparing Two Boosted Protease Inhibitor-based HAART Regimens in HIV-infected Patients Experiencing Their First Virologic Failure While Receiving an NNRTI-containing HAART Regimen

Safety, Tolerability, and Preliminary Efficacy Study of ALS-357 in Patients With Cutaneous Metastatic Melanoma

Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically Removed

Proteomic Profiling in Diagnosing Ovarian Cancer in Patients Who Are Undergoing Surgery for an Abnormal Pelvic Mass

Study to Determine the Digestive and Physiological Effects of an Extract From Bran in Healthy Men and Women

Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathy

Study Of SU011248 In Combination With Paclitaxel/Carboplatin In Patients With Advanced Solid Tumors

Study to Evaluate the Safety and Efficacy of Androxal™ Treatment in Men With Secondary Hypogonadism

Safety Study of XL999 in Adults With Non-Small-Cell Lung Cancer

Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene)

Study of HIV Patients With Undetectable Viral Load and Abnormal Lipids Switching to Atazanavir/Ritonavir

Post-Market Observational Study of Intra-Renal Drug Delivery

Study of XL999 in Adults With Solid Tumors