Clinical Trials in Chicago

Showing 1641-1660 of 20,493 trials

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

NCT04943848

This is a phase I, open label, plus expansion clinical trial evaluating the safety and tolerability of rHSC-DIPGVax in combination with BALSTILIMAB and ZALIFRELIMAB. rHSC-DIPGVax is an off-the-shelf neo-antigen heat shock protein containing 16 peptides reflecting neo-epitopes found in the majority of DIPG and DMG tumors. Newly diagnosed patients with DIPG and DMG who have completed radiation six to ten weeks prior to enrollment are eligible.

Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant

Ann & Robert H Lurie Children's Hospital of Chicago36 participantsStarted Jan 2022

Orange, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States

COMPLETEDNA2.2 miles

Noninvasive Spinal Stimulation in Stroke

NCT03714282

This is a randomized control trial that will evaluate the effectiveness of transcutaneous (non-invasive) spinal cord stimulation on gait and balance function for individuals with hemiplegia due to stroke.

Stroke

Shirley Ryan AbilityLab8 participantsStarted Oct 2018

Chicago, Illinois, United States

RECRUITING2.2 miles

Mucopolysaccharidosis VII Disease Monitoring Program

NCT03604835

The objectives of this study are to characterize MPS VII disease presentation and progression and assess long-term effectiveness and safety, including hypersensitivity reactions and immunogenicity of vestronidase alfa.

Mucopolysaccharidosis VIIMPS VIIMPS 7+1 more

Ultragenyx Pharmaceutical Inc50 participantsStarted Jan 2018

Orange, California, United States • Washington D.C., District of Columbia, United States • Chicago, Illinois, United States +11 more locations

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Noninvasive Spinal Stimulation in Stroke

Mucopolysaccharidosis VII Disease Monitoring Program

Find Trials by Condition in Chicago

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Radiation to Treat Joint Damage Caused by Cancer Immunotherapy

Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies

Evolut™ EXPAND TAVR II Pivotal Trial

A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

Safety and Efficacy Study of Transcatheter Closure of Ostium Secundum ASDs

A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma

A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control

A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Efficacy of the Dreem 3S Ambulatory Sleep Monitoring Device for the Evaluation of Narcolepsy

A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations

A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes

A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)

A Study to Compare the PK Characteristics, Safety, Tolerability, and Immunogenicity of HLX15-SC With DARZALEX FASPRO® in Combination With Lenalidomide and Dexamethasone (Rd) in Transplant-ineligible Patients With Newly Diagnosed Multiple Myeloma