Clinical Trials in Chicago

Showing 1181-1200 of 20,493 trials

EVR and EPO for Liver Transplant Tolerance

NCT06832189

This is an open label, single-arm, multicenter phase 1b study of stable adult liver transplant recipients on a tacrolimus (TAC)-based immunosuppression (IS) regimen who will transition from TAC to Everolimus (EVR), receive five doses of EPO and concurrently initiate phased withdrawal from EVR. The primary objective is to test the safety of administering Everolimus (EVR) and epoetin alfa (EPO) to induce operational tolerance in stable adult liver transplant recipients

Liver Transplant

National Institute of Allergy and Infectious Diseases (NIAID)20 participantsStarted Jan 2026

San Francisco, California, United States • Chicago, Illinois, United States • Philadelphia, Pennsylvania, United States

Active Not RecruitingPhase 32.2 miles

Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol

NCT00679042

In an earlier Phase 1/2 clinical trial using the Edmonton Protocol of steroid free immunosuppression, investigators at University of Illinois at Chicago (UIC) demonstrated the safety of islet preparation, iset transplantation, and medical treatment at UIC. Therefore, the primary purpose of the present Phase 3 clinical trial is to demonstrate the safety and efficacy of allogeneic islet transplantation in improving glycemic control in Type 1 diabetic patients using the UIC protocol that was developed and proven effective during the Phase 1/2 clinical trial.

Type 1 Diabetes Mellitus

CellTrans Inc.21 participantsStarted Sep 2007

Chicago, Illinois, United States

EVR and EPO for Liver Transplant Tolerance

Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol

Find Trials by Condition in Chicago

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Tocilizumab for Acute Chest Syndrome

Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults

A Study to Assess Adults With CIDP Transitioning From IVIg to Efgartigimod PH20 SC

RCT to Evaluate Social Skills in Children With Autism Using VR Technology (SoCaVR)

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

A Phase 2/3 Trial to Assess the Efficacy and Safety of OCU410ST for Stargardt Disease

A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

Women's Heart Attack Research Program: Stress Ancillary Study

A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes

A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma