Clinical Trials in Chicago

Showing 8501-8520 of 15,574 trials

HET Bipolar System: Validation of Outpatient Hemorrhoid Treatment

NCT02773420

Purpose: The current study aims to evaluate the safety and effectiveness of the HET™ Bipolar System (Medtronic, Boulder, CO) for the treatment of grade I-II hemorrhoids in a prospective pilot study. This device was evaluated retrospectively in a limited cohort of 23 patients previously. Methods: Patients seen at a colorectal clinic in a single institution with grade I-II hemorrhoids are offered to participate in a prospective pilot trial. The HET device is a modified anoscope equipped with LED lighting, a tissue clamping mechanism and a bipolar energy source used to treat multiple hemorrhoidal columns in one sitting. Three columns of hemorrhoids are treated with 2 heat energy applications per column. The primary outcome is the treatment effect on hemorrhoid symptoms of bleeding, pain, prolapse, itching, and soiling. This is measured with a patient completed questionnaire documenting each symptom's frequency from 0 to 3 (i.e. 0 is \< 1x/month; 3 is daily) before therapy and at 3 weeks and 6 month follow-up. Post-treatment pain scores were recorded using the visual analog scale (VAS).

Hemorrhoids

University of Illinois at Chicago35 participantsStarted Aug 2015

Chicago, Illinois, United States

COMPLETEDPhase 22.2 miles

Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches

NCT00172094

The purpose of this study was to evaluate the effectiveness and safety of a single oral dose of NPS 1776 in the acute treatment of migraine pain and associated symptoms.

Migraine Headache

Shire189 participantsStarted Dec 2003

Huntsville, Alabama, United States • Little Rock, Arkansas, United States • Oceanside, California, United States +19 more locations

HET Bipolar System: Validation of Outpatient Hemorrhoid Treatment

Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches

Find Trials by Condition in Chicago

2-Year Extension Study of Azeliragon in Subjects With Alzheimer's Disease (STEADFAST Extension)

The BEACON Study (Breast Cancer Outcomes With NKTR-102)

Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (CLI)

Spatz Adjustable Balloon for Obesity (SABO)

Lung-MAP: AZD4547 as Second-Line Therapy in Treating FGFR Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Anxiety Reduction During Office Procedural Medicine Using Aromatherapy

Safety and Tolerability Study of SHP465 in Children Aged 4 to 12 Years Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD)

Efficacy and Safety Study of DX-2930 to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE

A Study To Monitor Long-Term Treatment With PF-00547659

Study To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease

Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy

Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks

A Study of Atezolizumab in Advanced Solid Tumors

Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects

A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)

Safety and Efficacy of Bexagliflozin in Subjects With Moderate Hepatic Impairment

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301

CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12