Clinical Trials in California

Showing 1041-1060 of 11,359 trials

RECRUITING63 miles

Objective Assessment of Intraocular Lens Tilt and Decentration

NCT07324200

Prospective, multi-center, non-interventional, open label, randomized clinical study.

Tilt and Decentration

Johnson & Johnson Surgical Vision, Inc.80 participantsStarted Mar 2026

Bakersfield, California, United States • Sioux City, Iowa, United States

COMPLETEDPhase 1128 miles

Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract Infections

NCT05138822

This phase 1b study is a double-blind, double-dummy, nitrofurantoin-controlled study designed to evaluate microbiological response at the test of cure (ToC) visit along with safety, tolerability and pharmacokinetic (PK) response following oral dosing for 5 days of GSK3882347 in an adult female with uncomplicated urinary tract infections (uUTI). Comparator nitrofurantoin will be included in the study to ensure unbiased reporting of safety events. The study will be separated into 2 cohorts. Cohort 1 consists of an inpatient treatment period and PK analysis at frequent timepoints. Cohort 2 includes an outpatient treatment period and PK analysis conducted less frequently, at key trough timepoints.

Uncomplicated Urinary Tract InfectionsUrinary Tract Infections

GlaxoSmithKline140 participantsStarted May 2022

Anniston, Alabama, United States • Lomita, California, United States • Modesto, California, United States +12 more locations

Objective Assessment of Intraocular Lens Tilt and Decentration

Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract Infections

Find Trials by Condition in California

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

An International Observational Study of Adults With Acute Infection

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia

A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH)

Safety of RSV Preventive Monoclonal Antibody

A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)