Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
AstraZeneca
With
Eli Lilly and Company
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
HbA1c of 6.8% to 10.0%, inclusive.
Body mass index (BMI) of 25 kg/m\^2 to 40 kg/m\^2, inclusive.
You may not be if
Have participated in this study previously, or have received exenatide, pramlintide acetate, GLP-1 analogs, or dipeptidyl peptidase-IV (DPP-IV) inhibitors
Have participated in an interventional, medical, surgical, or pharmaceutical study (a study in which an experimental, drug, medical, or surgical treatment was given) within 30 days of study start. This criterion includes drugs that have not received regulatory approval for any indication at the time of study start.
Treated with any of the following medications:
* Thiazolidinedione within 5 months of screening;
* Sulfonylurea within 3 months of screening;
* Metformin/sulfonylurea combination therapy within 3 months of screening;
* Alpha-glucosidase inhibitor within 3 months of screening;
* Meglitinide within 3 months of screening;
* Insulin for more than 1 week within the 3 months prior to screening.
* Symlin (pramlintide acetate) injection or Byetta (exenatide) injection at any time
* Chronic (more than 2 weeks) or recent (within 4 weeks of study start) use of a drug that directly affects gastrointestinal motility
* Are receiving chronic (lasting longer than 2 weeks) systemic glucocorticoid therapy (excluding topical and inhaled preparations) or have received such therapy within the 4 weeks immediately preceding study start
* Regular use of a medication with addictive potential such as an opiate, narcotic, or tranquilizer
* Systemic antineoplastic agent
* Systemic transplantation medication
* Drugs for weight loss, including over-the-counter medications, within the 4 months prior to study start
