Clinical Trials in Baltimore

Showing 19741-19760 of 23,476 trials

Study to Assess the Safety and Tolerability of Ascending Single Doses of REGN2009 in Healthy Volunteers

NCT01893528

This is a phase 1, randomized, double-blind, placebo-controlled first-in-human (FIH) study to assess the safety and tolerability of ascending single doses of REGN2009 administered to healthy volunteers.

Healthy Volunteers

Regeneron Pharmaceuticals49 participantsStarted Jun 2013

Baltimore, Maryland, United States • Cincinnati, Ohio, United States

COMPLETEDPhase 1< 1 mile

A Phase I Study of AG-348 in Healthy Volunteers

NCT02149966

This is a dose escalation study that will be conducted in healthy volunteers. Multiple cohorts of volunteers will receive ascending (increasingly higher) oral doses of AG-348 daily for 14 days to evaluate the safety and tolerability of multiple oral doses of AG-348, the pharmacokinetics (PK) of multiple doses of AG-348, and the pharmacodynamic profile of AG-348 with specific biomarkers assessed in the blood.

Healthy Volunteer

Agios Pharmaceuticals, Inc.48 participantsStarted May 2014

Baltimore, Maryland, United States

COMPLETEDPhase 3< 1 mile

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

NCT01166542

The purpose of this Phase 3 study is to evaluate overall survival and progression free survival following intravenous administration of REOLYSIN (Reovirus Serotype 3 Dearing) in combination with paclitaxel and carboplatin versus chemotherapy treatment alone, in patients with metastatic or recurrent Squamous Cell Carcinoma of the Head and Neck.

Carcinoma, Squamous Cell of the Head and Neck

Oncolytics Biotech167 participantsStarted Jun 2010

Birmingham, Alabama, United States • Tucson, Arizona, United States • Burbank, California, United States +74 more locations

Study to Assess the Safety and Tolerability of Ascending Single Doses of REGN2009 in Healthy Volunteers

A Phase I Study of AG-348 in Healthy Volunteers

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

Find Trials by Condition in Baltimore

A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's Phenomenon

Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML

Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

Registry of AngioJet Use in the Peripheral Vascular System

A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring Hemodialysis

Responsive Feeding Study

Maraviroc in Rheumatoid Arthritis

Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors

An Exploratory Genetic Study in Participants With Psoriasis

Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

A Research Study to Treat Patients With Advanced Hepatocellular Carcinoma

Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina

A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus

Treatment Trial for Psychogenic Nonepileptic Seizures

ToGA Study - A Study of Herceptin (Trastuzumab) in Combination With Chemotherapy Compared With Chemotherapy Alone in Patients With HER2-Positive Advanced Gastric Cancer