Clinical Trials in Baltimore

Showing 16881-16900 of 23,476 trials

Safety of Riluzole in Patients With Acute Spinal Cord Injury

NCT00876889

The purpose of the study is to find out if the use of the drug Riluzole is both safe and improves outcome in patients with acute traumatic spinal cord injury (SCI).

Spinal Cord Injury

The Methodist Hospital Research Institute36 participantsStarted Apr 2010

Miami, Florida, United States • Louisville, Kentucky, United States • Baltimore, Maryland, United States +5 more locations

COMPLETEDPhase 4< 1 mile

A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis

NCT01042158

This will be a 36-week, single group, open label study assessing the effects of Tadalafil plus Ambrisentan combination therapy in patients with pulmonary arterial hypertension associated with the scleroderma spectrum of disease (PAH-SSD). Standard outcome measures such as six-minute walk distance (6MWD), New York heart Association (NYHA) classification, and hemodynamic measurements will be assessed, as well as novel functional measures of RV-PV function including the transthoracic echocardiogram parameter tricuspid annular plane systolic ejection (TAPSE), contrast-enhanced cardiac MRI and heart rate variability assessed by Holter monitoring. This design (excluding a placebo arm) was selected for ethical concerns and to provide optimal efficiency and active therapy to all study subjects. It also allows for comparisons between the two monotherapies and with combination therapy.

Pulmonary Arterial HypertensionSystemic SclerosisScleroderma Spectrum of Diseases+2 more

Johns Hopkins University25 participantsStarted Jan 2010

Baltimore, Maryland, United States

Safety of Riluzole in Patients With Acute Spinal Cord Injury

A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis

Find Trials by Condition in Baltimore

Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

MRD Testing Before and After Hematopoietic Cell Transplantation for Pediatric Acute Myeloid Leukemia

Antimicrobial Stewardship Through MRSA Diagnosis in Emergency Department (ED) Patients With Abscesses

GSK1605786A in the Maintenance of Remission in Subjects With Crohn's Disease

Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients

Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis

Safety and Tolerability Study of Larazotide Acetate in Celiac Disease Subjects

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

Randomized Study of Individualized Care Plans for Hematopoietic Cell Transplant Survivors

A Study of Guselkumab in Participants With Moderate to Severe Plaque-type Psoriasis and an Inadequate Response to Ustekinumab

A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed Dose Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder

Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation

Tubular Function in Asian-American Patients Receiving TDF or ETV for HBV Treatment

Healthy.io Method Comparison & User Performance Study

A Safety And Tolerability Study Of Valaciclovir Oral Suspension In Infants And Children

GSK2251052 in Complicated Urinary Tract Infection

A Study To Assess The Safety And Tolerability Of GSK189075 When Given With A Total Daily Dose Of >/ 2000mg of Metformin