Clinical Trials in Baltimore

Showing 9481-9500 of 23,476 trials

Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic Cancer

NCT02324543

This study will be looking at whether gemcitabine, taxotere, and xeloda (GTX) in combination with cisplatin and irinotecan is effective (anti-tumor activity) and safe in patients with metastatic pancreatic cancer.

Metastatic Pancreatic Adenocarcinoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins47 participantsStarted Feb 2015

Baltimore, Maryland, United States

COMPLETEDPhase 2< 1 mile

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

NCT01399372

RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some find cancer cells and help kill them or carry cancer-killing substances to them. Others interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as methotrexate, vincristine sulfate, procarbazine hydrochloride, and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high energy x rays to kill cancer cells. It is not yet know whether rituximab and combination chemotherapy are more effective when given with or without radiation therapy in treating patients with primary central nervous system lymphoma. PURPOSE: This randomized phase II trial studies how well giving rituximab and combination chemotherapy with or without radiation therapy works in treating patients with primary central nervous system lymphoma.

Chemotherapeutic Agent ToxicityCognitive/Functional EffectsLymphoma+2 more

Radiation Therapy Oncology Group91 participantsStarted Sep 2011

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Phoenix, Arizona, United States +42 more locations

Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic Cancer

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Find Trials by Condition in Baltimore

Vicinium Treatment for Subjects With Non-muscle Invasive Bladder Cancer Previously Treated With BCG

A Study to Investigate the Safety and Efficacy of Elsubrutinib and Upadacitinib Given Alone or in Combination in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE)

A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Hybrid Effectiveness-Implementation Study to Improve Clopidogrel Adherence

Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia

Cemented vs. Cementless Unicompartmental Knee Arthroplasty

Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy

Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) Patients

First in Human Study to Evaluate the Safety and Tolerability of EYP-1901 in Patients With Wet Age Related Macular Degeneration (wAMD)

Fingolimod in Preventing Paclitaxel-Associated Neuropathy in Patients With Breast Cancer

A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression

Registry for Proton Beam Radiation Therapy

Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis

Safety, Tolerability and Activity of SRX246 in Adults With Intermittent Explosive Disorder

Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity

Safety, PK and Efficacy of PCS12852 on Gastric Emptying Rate in Patients With Moderate to Severe Gastroparesis

Human Intravenous Interferon Beta-Ia Safety and Preliminary Efficacy in Hospitalized Subjects With COVID-19

Study to Investigate Efficacy, Safety and Pharmacokinetics of BT595 in Subjects With PID