Clinical Trials in Baltimore

Showing 2821-2840 of 11,213 trials

Clinical Trial of Approaches to Prostate Cancer Surgery

NCT05155501

This is a prospective, randomized controlled trial to compare cancer control and health-related quality of life following pelvic fascia-sparing radical prostatectomy versus standard radical prostatectomy. The investigators hypothesize that pelvic fascia-sparing radical prostatectomy will have similar cancer control (primary outcome) and sexual function outcomes; and significantly better urinary function, penile shortening/deformity and inguinal hernia risks as compared to radical prostatectomy.

Prostate Cancer

Weill Medical College of Cornell University600 participantsStarted May 2023

Washington D.C., District of Columbia, United States • Chicago, Illinois, United States • Baltimore, Maryland, United States +2 more locations

Active Not RecruitingPhase 3< 1 mile

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

NCT03710876

This study will evaluate intrapleural administration of Adenovirus-Delivered Interferon Alpha-2b (rAd-IFN) in combination with Celecoxib and Gemcitabine in patients with histologically confirmed Malignant Pleural Mesothelioma (MPM) who have failed a minimum of 1 treatment regimen and a maximum of 2 treatment regimens, 1 of which must have been an anti-folate and platinum combination regimen. Eligible patients will be randomized 1:1 to either: 1. Treatment group: rAd-IFN + Celecoxib followed by Gemcitabine 2. Control group: Celecoxib followed by Gemcitabine Patients randomized to the treatment group will receive rAd-IFN administered into the pleural space via an Intrapleural catheter (IPC) or similar intrapleural device on study Day 1. The primary objective of this study is to compare the overall survival (OS) associated with rAd IFN, when administered with celecoxib and gemcitabine, versus that associated with celecoxib and gemcitabine alone for the treatment of patients with MPM

Malignant Pleural Mesothelioma

Ferring Ventures Limited53 participantsStarted Jan 2019

Los Angeles, California, United States • San Francisco, California, United States • Tampa, Florida, United States +26 more locations

Clinical Trial of Approaches to Prostate Cancer Surgery

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

Find Trials by Condition in Baltimore

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM

Early Integrated Telehealth Versus In-Person Palliative Care for Patients With Lung Cancer

Human Immune Response to Ixodes Scapularis Tick Bites

Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy

A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML

An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation

A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

Engaging Patients to Promote Deprescribing

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial

Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

BCMA-directed CAR-T Cell Therapy in Adult Patients With Multiple Myeloma

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

Digital Support Systems to Improve Child Health and Development in Peru