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COMPLETEDPhase 2NCT05712421

A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism

The North Star study is a multi-center, Phase 2, double-blind, randomized, parallel group clinical study to evaluate the safe and effective dose conversion from Levothyroxine to North Star therapy.

Lead sponsor: Neuvosyn Laboratories, LLC•31 U.S. locations•View source on ClinicalTrials.gov

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 18, 2026Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE2

Enrollment303

Start dateFeb 2023

Last updatedFeb 18, 2026

Condition

Hypothyroidism

Locations shown

Neuvosyn Investigational Site

Birmingham, Alabama

Neuvosyn Investigational Site

Canoga Park, California

Neuvosyn Investigational Site

Greenbrae, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 18, 2026Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism

What this study is about

Save this trial guide to your notes

Sponsors

Related studies

Natural History of Thyroid Function Disorders

Physical Activity, Fatigue, Social Support, and Psychological Well-Being in Women With Primary Hypothyroidism

Thyroid Hormone Replacement After Coronary Artery Bypass Grafting for Patients With Subclinical Hypothyroidism

Ayurvedic Diet in Myxedema

Improvement of Laboratory Diagnostics in Hypothyroid Patients Using Levothyroxine

Trial snapshot

Condition

Locations shown

For caregivers