A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism

Exclusion Criteria

• •Any clinical condition or previous surgery that might affect the absorption, distribution, biotransformation or excretion of North Star or levothyroxine
• •Hospitalization for a major illness within 4 weeks prior to Screening
• •Anticipated initiation or change in concomitant medications
• •Concomitant use of prohibited medications or supplements
• •Participated in another investigational new drug study within 30 days or 5 half-lives of the IMP, whichever is longer, prior to the first study drug administration.
• •For female subjects, be pregnant, nursing or planning to become pregnant during the study