Clinical Trials in Austin

Showing 4981-5000 of 11,561 trials

FX-322 in Adults With Stable Sensorineural Hearing Loss

NCT04120116

This is a phase 2a single and repeat dose exploratory efficacy study of intratympanic FX-322 compared to placebo in healthy male and female adults with stable sensorineural hearing loss.

Sensorineural Hearing LossNoise Induced Hearing LossSudden Sensorineural Hearing Loss

Frequency Therapeutics95 participantsStarted Oct 2019

Fresno, California, United States • Torrance, California, United States • Colorado Springs, Colorado, United States +13 more locations

COMPLETEDPhase 2< 1 mile

Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE)

NCT03191864

Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus, characterized by eosinophilic infiltration and gastrointestinal symptoms. Swallowed, topically acting corticosteroids, such as fluticasone, appear to be effective in resolving acute clinical and pathological features of EoE. APT-1011 is an orally disintegrating tablet (ODT) formulation of fluticasone propionate. This study is designed to compare the efficacy and safety of APT-1011 with placebo in adults with EoE for an initial 12-week treatment period, followed by an additional 40-week maintenance treatment phase. Histologic response, pharmacokinetics, and dysphagia will be assessed.

Eosinophilic Esophagitis

Adare Pharmaceuticals, Inc.106 participantsStarted Jun 2017

Chandler, Arizona, United States • Tucson, Arizona, United States • Sherwood, Arkansas, United States +72 more locations

FX-322 in Adults With Stable Sensorineural Hearing Loss

Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE)

Find Trials by Condition in Austin

Randomized Trial in Adult Participants With Acute Migraines

A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)

First in Human Safety Study of FX-345 in Adults With Sensorineural Hearing Loss

Enhance Study: Evaluation of Accuracy and Safety of the Eversense CGM System With Enhanced Features

Safety, Tolerability, and Pharmacokinetics of CAL056 Mesylate in Patients With Resistant or Refractory Solid Tumors

A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143

A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer

A Study of TAK-951 to Stop Adults Getting Nausea and Vomiting After Planned Surgery

ErbB2 Over-expressing Metastatic Breast Cancer Study Using Paclitaxel, Trastuzumab, and Lapatinib

Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer

Relative Bioavailability of LY03010 Compared to Listed Drug

A 6-Month Study to Evaluate the Safety & Potential Efficacy of Trappsol Cyclo in Patients With Early Alzheimer's Disease

tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden

Rapid Diagnostics for HIV and Hepatitis

A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies

A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.