Clinical Trials in Arizona

Showing 6641-6660 of 12,706 trials

A First-in-Human Study of RPT193 in Healthy Volunteers and Patients With Atopic Dermatitis

NCT04271514

This study is a first-in-human, 3-part, multi-center, Phase 1, randomized, double-blind, placebo-controlled study with RPT193 in up to 64 healthy male and female subjects and 30 male and female patients with atopic dermatitis. RPT193 is an orally-available, potent, and selective antagonist of CCR4.

Atopic Dermatitis

RAPT Therapeutics, Inc.103 participantsStarted Aug 2019

Anniston, Alabama, United States • Scottsdale, Arizona, United States • San Diego, California, United States +11 more locations

COMPLETEDPhase 131 miles

Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)

NCT02001974

This is a phase I study to evaluate the safety and define the pharmacokinetic (PK) profile of orally administered reparixin in combination with paclitaxel in HER 2 (Human epidermal growth factor receptor-2) negative metastatic breast cancer patients. The primary objective of this study was to evaluate the safety and define the pharmacokinetic (PK) profile of orally administered reparixin in combination with paclitaxel in HER-2 negative MBC patients. The secondary objectives were to: 1. Evaluate the effects of orally administered reparixin on cancer stem cell (CSC) markers, the tumoral microenvironment and markers of cytokine inflammation; 2. Evaluate peripheral blood samples for enumeration of circulating tumor cells (CTCs), molecular characterization as CSCs and perform epithelial-mesenchymal transition (EMT) biomarker profiling; 3. Assess disease response for indication of efficacy.

Metastatic Breast Cancer

Dompé Farmaceutici S.p.A33 participantsStarted Feb 2012

Scottsdale, Arizona, United States • Fairway, Kansas, United States • Ann Arbor, Michigan, United States +2 more locations

A First-in-Human Study of RPT193 in Healthy Volunteers and Patients With Atopic Dermatitis

Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)

Find Trials by Condition in Arizona

Motions of the Bones and Activation of the Muscles of the Shoulder Girdle During Basic and Common Arm Movement

Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer

Infants Fed Extensively Hydrolyzed Casein-Based Infant Formulas

A Study of Immune Phenotype Biomarkers in Patients With Relapsing Multiple Sclerosis (RMS) After Treatment With 0.5mg Fingolimod

Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE)

A Phase 2 Study to Evaluate Immune Responses of FluMist®

Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer

Neoadjuvant GW572016 to Treat Breast Cancer

A Study of ALKS 3831 in Adults With Schizophrenia

Evaluation of Subchondroplasty™ for Defects Associated With Bone Marrow Lesions

Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease

Core Study of the Safety and Effectiveness of IDEAL IMPLANT(R) Saline-filled Breast Implants

Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Phase 2 Study of Zevalin Versus Zevalin and Motexafin Gadolinium in Patients With Rituximab-Refractory Low-grade or Follicular B-cell Non-Hodgkin's Lymphoma

Assessing Symptomatic Clinical Episodes in Depression

Effectiveness of Virtual Reality Gaming Therapy Versus CI Therapy for Upper Extremity Rehabilitation

Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study (TESTING Low Dose Study)