Ulcerative Colitis Clinical Trials

Showing 3381-3400 of 8,272 trials

Study of the Role of Pomegranate Juice Ellagitannins in the Modulation of Inflammation in Inflammatory Bowel Disease

NCT03000101

The aim of this research is to study the effects of a pomegranate juice on calprotectin levels in patients suffering of inflammatory bowel disease (IBD) in clinical remission. Fecal calprotectin levels, surrogate marker of mucosal inflammation, will be measured from baseline to 12 weeks later (end of intervention). Systemic and mucosal changes of biochemical and molecular inflammatory response markers will be also assessed.

Crohn's DiseaseUlcerative Colitis

IRCCS Azienda Ospedaliero-Universitaria di Bologna18 participantsStarted Jan 2017

Bologna, Italy

COMPLETEDPhase 1

A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis

NCT02985593

The objectives of this study are to evaluate the safety and tolerability of a single intravenous (IV) or subcutaneous (SC) dose of KHK4083 in Japanese or White healthy men in a placebo-controlled, single-blind comparative study, and to evaluate the safety and tolerability of multiple IV doses of KHK4083 in subjects with ulcerative colitis in an open-label study.

Healthy Men and Subjects With Ulcerative Colitis

Kyowa Kirin Co., Ltd.155 participantsStarted Dec 2016

Tokyo, Japan

COMPLETEDPhase 3

DE-117 Spectrum 5 Study

NCT03697811

Santen will evaluate the intraocular pressure (IOP) lowering effect and efficacy of DE-117 ophthalmic solution 0.002% in latanoprost low/non-responder subjects diagnosed with POAG or OHT

Primary Open-angle Glaucoma and Ocular Hypertension

Santen Inc.107 participantsStarted Sep 2018

Chandler, Arizona, United States • Glendale, California, United States • Mission Hills, California, United States +29 more locations

Study of the Role of Pomegranate Juice Ellagitannins in the Modulation of Inflammation in Inflammatory Bowel Disease

A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis

DE-117 Spectrum 5 Study

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