Ulcerative Colitis Clinical Trials

Showing 221-240 of 4,613 trials

Maternal-fetal Immune Responses to Fetal Surgery

NCT04484441

Performing surgery in utero on fetuses with certain birth defects has led to significant improvements in outcomes after birth; however, many of these infants are born preterm which can decrease the effectiveness of these procedures. The investigators aim to understand the effects of surgery on the maternal and fetal immune system and whether immune activation may be causing some of these infants to be born prematurely.

Spina BifidaCongenital Diaphragmatic HerniaLower Urinary Tract Obstructive Syndrome+1 more

Mayo Clinic21 participantsStarted Mar 2022

Rochester, Minnesota, United States • Cincinnati, Ohio, United States • Houston, Texas, United States

RECRUITINGPHASE1/PHASE2

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

NCT06128551

This study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated solid tumors.

Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma

Revolution Medicines, Inc.534 participantsStarted Nov 2023

Duarte, California, United States • Orange, California, United States • Sacramento, California, United States +50 more locations

Maternal-fetal Immune Responses to Fetal Surgery

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

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