Rheumatoid Arthritis Clinical Trials

Showing 17841-17860 of 47,334 trials

Tube Feeding in Children Having a Bone Marrow Transplant

NCT04804631

The purpose of this study is to assess the problems and a range of nutritional and clinical outcomes that occur with two feeding tubes used by children having a bone marrow transplant. Children and parents will also be interviewed to ask about their experiences of tube feeding.

Bone Marrow DiseaseStem Cell Transplant ComplicationsEnteral Feeding Intolerance+3 more

Institute of Child Health43 participantsStarted Mar 2021

London, United Kingdom

COMPLETEDPhase 3

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease

NCT02782741

Primary Objective: To determine the effect of avalglucosidase alfa treatment on respiratory muscle strength measured by percent (%) predicted forced vital capacity (FVC) in the upright position, as compared to alglucosidase alfa. Secondary Objective: To determine the safety and effect of avalglucosidase alfa treatment on functional endurance (6-minute walk test, inspiratory muscle strength (maximum inspiratory pressure), expiratory muscle strength (maximum expiratory pressure), lower extremity muscle strength (hand-held dynamometry), motor function (Quick Motor Function Test), and health-related quality of life (Short Form-12).

Glycogen Storage Disease Type II;Pompe's Disease

Genzyme, a Sanofi Company101 participantsStarted Nov 2016

Phoenix, Arizona, United States • Los Angeles, California, United States • Orange, California, United States +66 more locations

Tube Feeding in Children Having a Bone Marrow Transplant

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease

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