Rheumatoid Arthritis Clinical Trials

Showing 17041-17060 of 47,334 trials

Pectointercostal Block for Postoperative Pain Management After Sternotomy

NCT05552417

This randomized, controlled study is designed to assess the quality of analgesia provided by ultrasound-guided bilateral pectointercostal facial block in children undergoing cardiac surgery via midline sternotomy.

Post Operative Pain

Kasr El Aini Hospital60 participantsStarted Mar 2023

Cairo, Egypt

TERMINATEDPhase 4

Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease

NCT04311567

Pulmonary abnormalities are present in up to 60% of patients with early rheumatoid arthritis (RA), and up to 10% of the patients will develop clinical interstitial lung disease (ILD). Recent data indicate that inhibition of Janus kinase is beneficial for this extra-articular manifestation. Our goal is to determine whether tofacitinib is an effective and safe treatment, compared to standard-of-care methotrexate, for subclinical and clinical ILD in patients with early RA. The study also explores disease mechanisms in lungs and joints, to identify potential biomarkers for diagnosis, prognosis, and response to treatment of RA-ILD.

Rheumatoid ArthritisInterstitial Lung Disease Due to Systemic Disease (Disorder)RA+1 more

Vastra Gotaland Region3 participantsStarted Nov 2020

Lund, Skåne County, Sweden • Gothenburg, Västra Götaland County, Sweden • Stockholm, Sweden

Pectointercostal Block for Postoperative Pain Management After Sternotomy

Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease

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