Rheumatoid Arthritis Clinical Trials

Showing 14121-14140 of 47,334 trials

Efficacy Confirmation Study of CDP870 in Early Rheumatoid Arthritis

NCT01451203

The objective of this study is to assess the efficacy of certolizumab pegol (CZP) with methotrexate (MTX) compared with MTX-alone in patients with early-stage rheumatoid arthritis (RA) who are naive to MTX and have with poor prognostic factors, using inhibition of radiographically confirmed joint damage progression over a one-year period as a primary endpoint. Following a year of treatment with CZP plus MTX treatment, CZP will be discontinued, and the subjects will be monitored for one more year (the follow-up period) to investigate the sustainability of efficacy of CZP during the MTX monotherapy for exploratory purposes.

Rheumatoid Arthritis

Astellas Pharma Inc319 participantsStarted Oct 2011

Chubu Region, Japan • Chugoku Region, Japan • Hokkaido Region, Japan +5 more locations

COMPLETEDNA

Treatment of Periodontitis With Er:YAG Laser

NCT03628872

The purpose of this research project is to gain information on the best and most comfortable way to treat the periodontal disease. The main objective is to compare the efficacy of conventional scaling and root planning compared to laser scaling for the non-surgical treatment of periodontal disease. Both therapies have shown to be effective and are regularly used in the dental clinic.

Generalized Moderate Chronic PeriodontitisGeneralized Severe Chronic PeriodontitisPeriodontal Diseases

Columbia University29 participantsStarted Mar 2018

New York, New York, United States

Efficacy Confirmation Study of CDP870 in Early Rheumatoid Arthritis

Treatment of Periodontitis With Er:YAG Laser

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