Rheumatoid Arthritis Clinical Trials

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Cognitive Screening of Patients with Hearing Loss

NCT04672174

Hearing loss and cognitive impairment both appear in elderly patients. The goal was to use a modified screening method added to already established cognitive tests to obtain a standardized test for detection of cognitive impairment in patients with hearing loss. The aim of this study is to collect data with neuropsychological tests using questionnaires and to determine cognitive impairment in patients with hearing loss. The collected data will be evaluated using SPSS 23. The corrected item-total correlation and item difficulty of the item DemTectEar will be assessed by item analysis / Cronbachs' Alpha. For further evaluation and comparisons two-sided t-tests with a level of significance 0.05 or Mann-Whitney-U-tests will be performed.

Hearing Loss, Sensorineural

University of Zurich20 participantsStarted Nov 2019

Zurich, Canton of Zurich, Switzerland

TERMINATEDPhase 1

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

NCT04925206

This is a single-arm, open label, multi-center, single-dose phase 1 study in subjects with transfusion dependent β-thalassaemia. The study will evaluate the safety and efficacy of autologous CRISPR-Cas9 Modified CD34+ Human Hematopoietic Stem and Progenitor Cells (hHSPCs) using ET-01.

Transfusion Dependent Beta-Thalassaemia

EdiGene (GuangZhou) Inc.8 participantsStarted Aug 2021

Guangzhou, Guangdong, China • Guangzhou, Guangdong, China • Shenzhen, Guangdong, China +1 more locations

Active Not RecruitingNA

Repeated Low-Level Red-Light Therapy for Shortening Axial Length

NCT05550740

The purpose of this clinical trial is to confirm the incidence and magnitude of axial length shortening after RLRL therapy in Chinese high myopia children and teenagers.

High MyopiaRefractive ErrorsEye Diseases

Shanghai Eye Disease Prevention and Treatment Center30 participantsStarted Nov 2022

Shanghai, Shanghai Municipality, China

Cognitive Screening of Patients with Hearing Loss

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Repeated Low-Level Red-Light Therapy for Shortening Axial Length

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