Rheumatoid Arthritis Clinical Trials

Showing 5341-5360 of 47,334 trials

A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM

NCT04622046

This prospective study is designed to evaluate the efficacy, safety, and tolerability of ALXN2060 (also known as AG10), as well as to establish its pharmacokinetic and pharmacodynamic profile in Japanese participants with symptomatic ATTR-CM administered on a background of stable heart failure therapy.

Symptomatic Transthyretin Amyloid Cardiomyopathy

Alexion Pharmaceuticals, Inc.25 participantsStarted Nov 2020

Bunkyō City, Japan • Fukuoka, Japan • Kumamoto, Japan +8 more locations

Active Not RecruitingPhase 1

Tegavivint for the Treatment of Relapsed or Refractory Leukemia

NCT04874480

This phase I trial is to find out the best dose and side effects of tegavivint in treating patients with leukemia that has come back (relapsed) or does not response to treatment (refractory). Tegavivint may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving tegavivint in combination with decitabine may help control the disease.

Recurrent LeukemiaRefractory Leukemia

M.D. Anderson Cancer Center9 participantsStarted Sep 2021

Houston, Texas, United States

RECRUITINGPhase 4

Liposomal and Standard Bupivacaine in Thoracic Paravertebral Block for Post-Thoracoscopic Pain

NCT06165991

I. Research purpose 1.1 Main Objective: To investigate the efficacy and safety of bupivacaine liposome thoracic paravertebral nerve block for postoperative analgesia after thoracoscopic lobectomy 1.2 Exploratory Objective: To investigate the noninferiority of bupivacaine liposomes in thoracic paravertebral nerve block with standard bupivacaine

Thoracic Paravertebral BlockPostoperative AnalgesiaThoracoscopic Lobectomy

Yongtao Sun496 participantsStarted Jun 2024

Jinan, Shandong, China

A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM

Tegavivint for the Treatment of Relapsed or Refractory Leukemia

Liposomal and Standard Bupivacaine in Thoracic Paravertebral Block for Post-Thoracoscopic Pain

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