Rheumatoid Arthritis Clinical Trials

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A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-079 Administered Subcutaneously as a Single Agent in Participants With Relapsed/Refractory (r/r) Multiple Myeloma (MM)

NCT03439280

The purpose of this study is to assess the safety and tolerability, maximum tolerated dose (MTD)/recommended phase 2 dose (RP2D) of TAK-079 monotherapy and when combined with a backbone regimen of pomalidomide and dexamethasone (PomDex) in Phase 1, and to provide a preliminary evaluation of the clinical activity of TAK-079 monotherapy in Phase 2a in participants with r/r MM.

Relapsed/RefractoryMultiple Myeloma

Millennium Pharmaceuticals, Inc.50 participantsStarted Apr 2018

Duarte, California, United States • St Louis, Missouri, United States • New York, New York, United States +4 more locations

UNKNOWNNA

Opioid-free Anesthesia in Laparoscopic Cholecystectomies

NCT05089526

The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic cholecystectomies

Pain, PostoperativePain, AcutePain, Chronic+8 more

Aretaieion University Hospital70 participantsStarted Oct 2021

Athens, Greece

A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-079 Administered Subcutaneously as a Single Agent in Participants With Relapsed/Refractory (r/r) Multiple Myeloma (MM)

Opioid-free Anesthesia in Laparoscopic Cholecystectomies

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