Rheumatoid Arthritis Clinical Trials

Showing 21761-21780 of 47,334 trials

COLLISION RELAPSE Trial

NCT05861505

The primary objective is to demonstrate superiority of neoadjuvant systemic therapy followed by repeat local treatment as compared to upfront repeat local treatment in patients with at least one locally treatable recurrent CRLM in the absence of extrahepatic disease.

Colorectal CancerLiver MetastasesLiver Metastasis Colon Cancer+3 more

Amsterdam UMC, location VUmc360 participantsStarted Apr 2023

Amsterdam, Netherlands

UNKNOWNPhase 4

The Study of Vidicizumab Combined With Tirelizumab in the Treatment of Breast Cancer With Low HER2 Expression

NCT05861635

To evaluate the efficacy and safety of vidicizumab combined with tirelizumab in the treatment of early high-risk or locally advanced breast cancer with low HER2 expression

Breast CancerNeoadjuvant Therapy

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology42 participantsStarted Feb 2023

Wuhan, Hubei, China

RECRUITING

Immune Biomarker Study for Head and Neck Cancer

NCT05375266

The aim of this prospective non-interventional multi-center trial is to study the prognostic value of intratumoral and systemic immune biomarkers in newly diagnosed non-metastatic head and neck cancer. Furthermore, the local immunological processes in the tumor will be correlated with the systemic immune status determined in the peripheral blood to identify prognostic immune signatures. In addition, tumor organoids will be generated ex vivo for functional biological analyses. The main objective is to create a prognostic score determined by clusters based on tumor immunologic criteria.

Head and Neck CancerOral Cavity CancerOropharyngeal Cancer+2 more

University of Erlangen-Nürnberg Medical School1,100 participantsStarted May 2022

Erlangen, Bavaria, Germany • Erlangen, Bavaria, Germany • Erlangen, Bavaria, Germany

COLLISION RELAPSE Trial

The Study of Vidicizumab Combined With Tirelizumab in the Treatment of Breast Cancer With Low HER2 Expression

Immune Biomarker Study for Head and Neck Cancer

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