Loading clinical trials...

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture | Clinical Trials | Clareo Health

RECRUITINGPHASE4

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Percutaneous Needle Fasciotomy (PNF) +/- Corticosteroid Injection for Dupuytren's Contracture (DC) Affecting Metacarpophalangeal Joints (MCP) . A Randomized Controlled Trial

NCT05440240•Regionshospitalet Silkeborg

View on ClinicalTrials.gov

Summary

Comparing percutaneous needle fasciotomy +/- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.

Eligibility

Age

45 - 99 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Sufficient correction of metacarpophalangeal (MCP) joint during the PNF treatment, defined as \<20° passive extension deficit (PED), is a prerequisite for inclusion.
•Dupuytren contracture (DC) of ≥ 20° PED in MCP joint measured with a goniometer
•DC of either II-V finger
•Well-defined/palpable cord

Exclusion Criteria

•Legally incapacitated
•Previous study inclusion with another finger ray
•Isolated proximal interphalangeal (PIP) or distal interphalangeal (DIP) joint contracture, defined as MCP joint contracture \< 20° PED regardless of the deficit in the PIP or DIP joint
•Previous hand surgery of the affected finger for any reason
•Known allergy to the study medication
•Anticoagulant therapy (Acetylsalicylic acid is NOT an exclusion criterion)
•Pregnant or lactation
•Insulin dependent diabetes mellitus
•Ongoing systemic infection or local infection at the site of the procedure
•Rheumatoid arthritis
+2 more criteria

Locations (1)

Silkeborg Regional Hospital

Silkeborg, Denmark

Key Dates

Start Date

January 10, 2023

Primary Completion Date

December 1, 2025

Completion Date

March 1, 2030

Last Updated

May 17, 2023

Enrollment

400

ESTIMATED participants

Conditions

Dupuytren ContractureDupuytren's DiseaseContractureJoint DiseasesMusculoskeletal DiseasesFibromaNeoplasm, Fibrous TissueNeoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsConnective Tissue Diseases

Interventions

Percutaneous needle fasciotomy

PROCEDURE

Corticosteroid injection

DRUG

Saline injection

OTHER

Contacts

Laura H Matthiesen, MS, PhD-student

CONTACT

004561281917 lather@rm.dk

Jeppe Lange, MD, PhD

CONTACT

jepplang@rm.dk

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

NCT05945329

Capsular Contracture Associated With Breast ImplantCapsular Contracture Grade III+1 more

View study

RECRUITINGNA

Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease

NCT05067764

Dupuytren's Disease

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 17, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Inclusion Criteria

Exclusion Criteria

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease

Dynamic Stretching vs. Foam Rolling: Effects on Hamstring Flexibility and Muscle Oxygenation in Tight Hamstrings

Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test

Nylon Versus Chromic Gut Sutures for Minor Hand Surgery