Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1721-1740 of 3,347 trials

(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies

NCT02561988

This is a Phase 1, open-label, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antineoplastic activity of avapritinib (also known as BLU-285), administered orally (PO), in adult patients with advanced systemic mastocytosis and other relapsed or refractory myeloid malignancies. The study consists of 2 parts:, dose-escalation (Part 1) and expansion (Part 2).

Aggressive Systemic MastocytosisSystemic Mastocytosis-associated Hematologic Non-mast Cell DiseaseMast Cell Leukemia+1 more

Blueprint Medicines Corporation86 participantsStarted Mar 2016

Stanford, California, United States • Denver, Colorado, United States • Atlanta, Georgia, United States +8 more locations

COMPLETED< 1 mile

Streamlining Trauma Research Evaluation With Advanced Measurement

NCT02079714

The STREAM Study is a prospective longitudinal observational outcomes study that will examine the reliability, validity and responsiveness of the PROMIS tools for clinical research following orthopaedic trauma.

Orthopaedic Trauma

Major Extremity Trauma Research Consortium1,065 participantsStarted Jan 2014

Birmingham, Alabama, United States • San Diego, California, United States • San Francisco, California, United States +41 more locations

(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies

Streamlining Trauma Research Evaluation With Advanced Measurement

Rheumatoid Arthritis Trials in Other Cities

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation

Dose Ranging Study of Rimegepant (BMS-927711) for the Acute Treatment of Migraine

Expanded Access Protocol Using 131I-MIBG

MORE-PC: A 30-day Automated SMS Program to Support Post-discharge Transitions of Care

Trial in Adult Subjects With Acute Migraines

Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

Assessment of Safety and Efficacy of Nerivio for the Migraine Prevention

Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension

A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-079 Administered Subcutaneously as a Single Agent in Participants With Relapsed/Refractory (r/r) Multiple Myeloma (MM)

Safety and Efficacy in Adult Subjects With Acute Migraines

Bacteriophage Therapy in Patients With Urinary Tract Infections

A Study of ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity

First-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express Mesothelin

Study of the Safety and Efficacy of APX3330 in Diabetic Retinopathy

Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition

Other Conditions in Philadelphia