Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1981-2000 of 3,347 trials

Early FDG PET in Melanoma

NCT02716077

Adult patients with histologically proven melanoma who will be treated with pembrolizumab will undergo FDG PET/CT scan as an early evaluation of response to therapy. Changes in FDG uptake will be correlated with lab and pathology results.

Clinical Stage III Nodal or Intransit Disease or Resectable Stage IV Melanoma

Abramson Cancer Center at Penn Medicine6 participantsStarted Mar 2016

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 213 miles

PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations

NCT03609619

This is PART B of a 2-part, 6-week, double-blind, dose-optimization, parallel-group study in children and adolescents (ages 6-17 years) with ADHD with and without CNVs in specific genes implicated in glutamatergic signaling and neuronal activity. PART B will assess subjects who do not have CNVs in any of the specific gene mutation(s) implicated in glutamatergic signaling and neuronal connectivity.

Attention Deficit Hyperactivity Disorder

Aevi Genomic Medicine, LLC, a Cerecor company109 participantsStarted Aug 2018

Wayne, Pennsylvania, United States

COMPLETEDPhase 213 miles

PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations

NCT03265119

This is PART A of a 2-part, 6-week, double-blind, dose-optimization, parallel-group study in children and adolescents (ages 6-17 years) with ADHD with and without CNVs in specific genes implicated in glutamatergic signaling and neuronal activity. Parts A will include subjects determined to have a specific gene mutations implicated in glutamatergic signaling and neuronal connectivity.

Attention Deficit Hyperactivity Disorder

Aevi Genomic Medicine, LLC, a Cerecor company69 participantsStarted Aug 2017

Wayne, Pennsylvania, United States

Early FDG PET in Melanoma

PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations

PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations

Rheumatoid Arthritis Trials in Other Cities

A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD)

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects

A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone

Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer

A Study to Evaluate Safety and Efficacy of Panobinostat in Participants With Primary Myelofibrosis

Study of IL-22 IgG2-Fc (F-652) for Subjects With Grade II-IV Lower GI aGVHD

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Disease

Role of Rehabilitation in Concussion Management: A Randomized Controlled Trial

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors

A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors

Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration Subjects

Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Posterolateral Thoracotomy

Breast Mesh Used in Two-staged Breast Reconstruction

Other Conditions in Philadelphia