Rheumatoid Arthritis Clinical Trials in Los Angeles

Showing 3021-3040 of 3,190 trials

Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?

NCT01210079

Utilizing a double-blind, placebo-controlled design, the proposed work will evaluate the ability of an adjuvant anticonvulsant analgesic to diminish or reverse the opioid-induced hyperalgesia complicating the pain states suffered by Methadone-Maintained (MM) patients. Specifically, in a sample of MM patients, gabapentin, which has proven efficacy in treating neuropathic pain will be evaluated for its ability to ameliorate or diminish the opioid-induced hyperalgesia in these patients as reflected by changes on pain threshold and tolerance to both cold-pressor and electrical pain, at peak and through methadone blood levels. The results of this work will not only provide pharmacologic insight into the mechanisms underlying poor pain tolerance in this at-risk population, but also direction for the medical management of pain complicated by opioid-induced hyperalgesia.

Opioid-Induced Hyperalgesia

University of California, Los Angeles26 participantsStarted Sep 2002

Los Angeles, California, United States

TERMINATEDPhase 28.7 miles

Dose Finding Posterolateral Thoracotomy Study

NCT00807209

To review safety and effectiveness of two doses compared to current standard of care.

Postoperative Pain

Pacira Pharmaceuticals, Inc3 participantsStarted Dec 2008

Pasadena, California, United States • Orlando, Florida, United States • Houston, Texas, United States +2 more locations

Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?

Dose Finding Posterolateral Thoracotomy Study

Rheumatoid Arthritis Trials in Other Cities

Intravitreal LFG316 in Patients With Advanced Age-related Macular Degeneration

Study To Evaluate Upper Arm Autologous Fat Transfer

Safety and Efficacy Study of Isolagen Therapy in the Treatment of Nasolabial Fold Wrinkles

Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis

Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

Trial of a Secondary Stroke Prevention Program

Expanding and Testing VA Collaborative Care Models for Depression

A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy

Study of Levalbuterol and Racemic Albuterol in Pediatric Subjects With Reactive Airways Disease (RAD)

The Efficacy of Stellate Ganglion Block as Post-traumatic Stress Disorder (PTSD) Therapy: A Pilot Study

A Pilot Study to Evaluate The Efficacy of Adapalene 0.3% for Use in the Prevention and Treatment of Senile Purpura

Radiographic and Intravascular (IVUS) Evaluation of Venous Morphology During CCSVI Treatment

Safety and Efficacy Study of Isolagen TherapyTM in the Treatment of Nasolabial Fold Wrinkles

Study to Assess Efficacy of Tacrolimus + Methotrexate Versus Placebo + Methotrexate in Treatment of Rheumatoid Arthritis

Study Evaluating the Effect of Sirolimus on Non-Melanoma Skin Cancer in Kidney Transplant Recipients

Evaluating the Ability of Zoledronic Acid to Reduce the Rate of Subsequent Osteoporotic Fractures After a Hip Fracture

FACTS II: A Study to Test the Safety and Effectiveness of a New Medication on the Treatment of Active Ulcerative Colitis

Study of Urgent PC Versus Sham Effectiveness in Treatment of Overactive Bladder Symptoms

Other Conditions in Los Angeles