PTSD Clinical Trials

Showing 81-100 of 229 trials

Hyperbaric Oxygen Therapy for Adult Onset Post Traumatic Stress Disorder

NCT03466554

Posttraumatic stress disorder (PTSD) is the long term effect of severely distressing traumatic event characterized by intrusive thoughts, nightmares, and avoidance. Brain imaging of PTSD patients demonstrate alterations in regional brain perfusion, with stunned, hypoperfused regions. Those brain-biological pathologies may be responsible for the limited success rate of currently available interventions. During the last years data regarding Hyperbaric Oxygen Therapy (HBOT) induced neuroplasticity accumulated. A number of studies in traumatic brain injury, cerebrovascular attacks, and fibromyalgia have presented evidence of improved perfusion and recovery of metabolic brain tissues, accompanied by clinical improvement under HBOT even years after the acute insults. Considerable evidence supports potential benefit of HBOT on PTSD, however, no clinical trial was done on this pure PTSD population. The aim of the proposed study is to examine hyperbaric oxygen therapy as a treatment for PTSD. Advanced brain imaging and functional analysis tools will be used to evaluate treatment's effect.

Ptsd

Assaf-Harofeh Medical Center30 participantsStarted Mar 2018

Ẕerifin, Israel

COMPLETEDNA

The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans

NCT03521999

Behavioral health problems among Veterans have raised awareness of the critical need for more reliable, effective, and accessible ways to recognize those in need, direct them to help, and ensure that they receive the best evidence-based care available. AboutFace is a novel peer education program that features the personal stories of Veterans and is designed to improve Veterans' likelihood of engaging in Post Traumatic Stress Disorder (PTSD) specialty care. Using a randomized controlled study design the investigators propose to compare the efficacy of AboutFace relative to standard care for improving treatment engagement and outcomes. Additional data from VA providers will provide valuable information on wide scale implementation and dissemination of AboutFace. If AboutFace increases access of services, data will have broad implications for overcoming barriers to care for Veterans with PTSD and other stigmatized conditions.

PTSDPosttraumatic Stress Disorder

VA Office of Research and Development330 participantsStarted Aug 2018

Charleston, South Carolina, United States

Hyperbaric Oxygen Therapy for Adult Onset Post Traumatic Stress Disorder

The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans

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