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Clareo Health | Prostate Cancer Clinical Trials in Pittsburgh | 219 Studies

Clinical Trials Prostate CancerPittsburgh

Prostate Cancer Clinical Trials in Pittsburgh

Find 219 clinical trials for prostate cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Prostate Cancer trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 219 trials

Active not recruitingPhase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)The main objective of the study is to compare overall survival in participants receiving xaluritamig versus investigator's choice (cabazitaxel or second androgen receptor-directed…NCT06691984·Birmingham, Alabama and 163 others

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Data from ClinicalTrials.govTerms

Active not recruitingTesting the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate CancerThis phase II trial tests how well M1774 works in treating patients with prostate cancer that does not respond to treatment (refractory) and that has a mutation in the gene…NCT05828082·Phoenix, Arizona and 25 others

Active not recruitingAntiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by SurgeryThis randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy…NCT03070886·Mobile, Alabama and 312 others

CompletedObservational Study of Docetaxel Exposure in Metastatic Prostate Cancer PatientsIn this observational study, blood samples for pharmacokinetic (PK) testing will be collected from subjects with metastatic prostate cancer during their treatment with docetaxel.NCT02376296·Beaver, Pennsylvania and 19 others

RecruitingStandard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate CancerThis phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants…NCT03678025·Gilbert, Arizona and 337 others

Active not recruitingTTX-080 HLA-G Antagonist in Subjects With Advanced CancersTTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy…NCT04485013·Tucson, Arizona and 40 others

Active not recruitingA Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate CancerThe purpose of this study is to: a) establish the recommended phase 2 dose (RP2D) and to evaluate the antitumor activity and safety of niraparib combination therapies…NCT03431350·Tucson, Arizona and 49 others

Completed"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased RiskThis 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are…NCT00056407·Birmingham, Alabama and 931 others

RecruitingThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or…NCT04585750·Irvine, California and 76 others

CompletedThalidomide and Doxil® in Patients With Androgen Independent Prostate Cancer (AIPC)The primary objective of this study is to evaluate PSA response rates of the combination of Doxil and Thalidomide in patients with AIPC who have failed chemotherapy.NCT00307294·Pittsburgh, Pennsylvania

CompletedCalcitriol and Dexamethasone in Treating Patients With Prostate Cancer Who Have Undergone Surgery or Radiation TherapyRATIONALE: Calcitriol may help tumor cells develop into normal cells. Dexamethasone may increase the effectiveness of calcitriol by making tumor cells more sensitive to the drug.NCT00054522·Buffalo, New York and 1 other

Active not recruitingTalazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPCThis study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with…NCT03395197·Anchorage, Alaska and 369 others

CompletedA Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate CancerThe purpose of this study is to assess the safety and effectiveness of nivolumab with docetaxel in men with advanced castration resistant prostate cancer who have progressed after…NCT04100018·Mobile, Alabama and 292 others

CompletedA Study of Enzalutamide and LY3023414 in Men With Prostate CancerThe main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in men with prostate cancer.NCT02407054·Homewood, Alabama and 35 others

TerminatedA Study of CART-PSMA-TGFβRDN in Patients With Metastatic Castration Resistant Prostate CancerMulti-center, open-label, Phase 1 study of the safety, tolerability and feasibility of dosing patients harboring metastatic castration resistant prostate cancer (mCRPC) with…NCT04227275·Tampa, Florida and 8 others

CompletedA Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid TumorsThis will be a Phase 1, open label, 2-sequence, crossover study to establish the BE of the current commercial formulation (Generation 3.1 talazoparib capsules) to the proposed…NCT04672460·Encinitas, California and 30 others

CompletedBicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate CancerThis phase II trial studies how well giving bicalutamide with or without Akt inhibitor MK2206 works in treating patients with previously treated prostate cancer.NCT01251861·Palo Alto, California and 197 others

RecruitingThe MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac StudyThe Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based…NCT04075305·Pittsburgh, Pennsylvania and 17 others

CompletedCPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced CancersThis is a Phase 1/1b open-label, dose escalation and dose expansion study of CPI-006, a humanized monoclonal antibody (mAb) targeting the CD73 cell-surface ectonucleotidase in…NCT03454451·Tucson, Arizona and 26 others

TerminatedSunitinib Plus Prednisone In Patients With Metastatic Castration-Resistant Prostate Cancer After Failure Of Docetaxel ChemotherapyThis study will compare the safety and efficacy of sunitinib in combination with prednisone versus placebo and prednisone in patients that have metastatic castration-resistant…NCT00676650·Decatur, Alabama and 204 others

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