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Clareo Health | Prostate Cancer Clinical Trials in Pennsylvania | 626 Studies

Clinical Trials Prostate CancerPennsylvania

Prostate Cancer Clinical Trials in Pennsylvania

Find 626 clinical trials for prostate cancer near Pennsylvania. Connect with research centers in your area.

All Prostate Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 501-520 of 626 trials

CompletedDocetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone TherapyRATIONALE: Androgens can stimulate the growth of prostate cancer cells. Estramustine may fight prostate cancer by reducing the production of androgens.NCT00052845·Anniston, Alabama and 79 others

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Data from ClinicalTrials.govTerms

CompletedS0421, Docetaxel and Prednisone With or Without Atrasentan in Treating Patients With Stage IV Prostate Cancer and Bone Metastases That Did Not Respond to Previous Hormone TherapyRATIONALE: Drugs used in chemotherapy, such as docetaxel, prednisone, and atrasentan work in different ways to stop the growth of tumor cells, either by killing the cells or by…NCT00134056·Mobile, Alabama and 553 others

RecruitingStudy of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsThis is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity…NCT05176483·Phoenix, Arizona and 121 others

TerminatedStudy to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)Researchers in this study want to compare the effects of drug darolutamide and drug enzalutamide on physical function, including balance and daily activity, in patients with…NCT04157088·Portland, Maine and 6 others

RecruitingA Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)The purpose of this study is to assess the efficacy and safety of opevesostat plus daily corticosteroids compared to alternative abiraterone acetate or enzalutamide in…NCT06136650·Tucson, Arizona and 329 others

Active not recruitingA Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPCThe purpose of this study is to determine if the addition of apalutamide to ADT provides superior efficacy in improving radiographic progression-free survival (rPFS) or overall…NCT02489318·Homewood, Alabama and 219 others

TerminatedExpanded Access Study of Satraplatin Plus Prednisone in Patients With Hormone Refractory Prostate Cancer (HRPC)The SPERA trial is designed to 1. provide satraplatin to physicians with patients who have hormone refractory prostate cancer (HRPC) which has progressed following unlimited…NCT00450970·Birmingham, Alabama and 120 others

RecruitingA Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid TumorsThe goal of this clinical trial is to test a new medicine called GSK5764227, which delivers a toxin directly to cancer cells to destroy them while sparing healthy cells.NCT07277270·Reunion, Florida and 21 others

Active not recruitingAn Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)This Phase II study aims to evaluate efficacy and safety of the combination of JSB462 (also known as luxdegalutamide) at 100 mg and 300 mg once a day (QD) doses + abiraterone…NCT06991556·La Jolla, California and 65 others

CompletedPreliminary Evaluation of Uptake of [68Ga]P16-093 in Metastatic Prostate and Renal CancerAn phase I study to evaluate the uptake of \[68Ga\]P16-093 in known or suspected metastatic prostate or renal cancer to establish the feasibility of using \[68Ga\]P16-093 to image…NCT03073395·Philadelphia, Pennsylvania

CompletedStudy of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100This study will evaluate the effect of cabozantinib compared to prednisone on overall survival in men with previously treated metastatic castration-resistant prostate cancer with…NCT01605227·Birmingham, Alabama and 263 others

Active not recruitingA Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).Pfizer MEVPRO-1 (C2321014) is a randomized, open-label, multi-center clinical trial evaluating whether combining the study medicine (PF-06821497) with enzalutamide is safe and…NCT06551324·Homewood, Alabama and 223 others

CompletedPrevention of Osteoporosis in Men With Prostate CancerThe purpose of this two year study is to examine the safety and effectiveness of alendronate (Fosamax) for the prevention of bone loss in men with prostate cancer who are on…NCT00048841·Pittsburgh, Pennsylvania

RecruitingStandard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate CancerThis phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants…NCT03678025·Gilbert, Arizona and 337 others

CompletedPhysician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage CancerRATIONALE: Physician-initiated smoking cessation strategies may be effective in getting early-stage cancer patients to quit smoking.NCT00002520·Philadelphia, Pennsylvania

RecruitingBarrigel® PPRT (Post-Prostatectomy Radiation Therapy) TrialBarrigel is intended to temporarily position the anterior rectal wall away from the prostate or prostate bed during radiotherapy treatment for prostate cancer and, in creating…NCT06496256·Chandler, Arizona and 12 others

CompletedVinflunine in Hormone Refractory Prostate Cancer (HRPC)Currently, there are no established 2nd-line or salvage chemotherapy regimens for patients with HRPC, many of whom retain an excellent performance status.NCT00545766·Fort Myers, Florida and 11 others

RecruitingStudy of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)This is a phase 3, randomized, open-label study of opevesostat compared to alternative abiraterone acetate or enzalutamide in participants with metastatic castration-resistant…NCT06136624·Orange, California and 287 others

CompletedA Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid MalignanciesThis is a Phase 1, open-label, multicenter study of continuous oral dosing of AZD4635 administered to patients with advanced solid malignancies.NCT02740985·Fayetteville, Arkansas and 16 others

Active not recruitingOlaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker AnalysisOlaparib has demonstrated preliminary efficacy in metastatic castration-resistant prostate cancer.NCT03047135·Baltimore, Maryland and 3 others

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