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Clareo Health | Prostate Cancer Clinical Trials in Pennsylvania | 623 Studies

Clinical Trials Prostate CancerPennsylvania

Prostate Cancer Clinical Trials in Pennsylvania

Find 623 clinical trials for prostate cancer near Pennsylvania. Connect with research centers in your area.

All Prostate Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 421-440 of 623 trials

Completed18F Fluciclovine (FACBC) PET/CT in Patients With Rising PSA After Initial Prostate Cancer TreatmentThis prospective study will enroll up to 330 men with PSA-persistent or PSA-recurrent prostate cancer after curative-intent primary therapy and negative or equivocal findings on…NCT02680041·Duarte, California and 16 others Not yet recruitingMultiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate CancerThis phase III trial compares the use of contrast-enhanced multiparametric ultrasound (mp-US) to multiparametric magnetic resonance imaging (mp-MRI) for the diagnosis of…NCT06024772·Philadelphia, Pennsylvania and 1 other

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Data from ClinicalTrials.govTerms

CompletedThalidomide and Doxil® in Patients With Androgen Independent Prostate Cancer (AIPC)The primary objective of this study is to evaluate PSA response rates of the combination of Doxil and Thalidomide in patients with AIPC who have failed chemotherapy.NCT00307294·Pittsburgh, Pennsylvania

CompletedCalcitriol and Dexamethasone in Treating Patients With Prostate Cancer Who Have Undergone Surgery or Radiation TherapyRATIONALE: Calcitriol may help tumor cells develop into normal cells. Dexamethasone may increase the effectiveness of calcitriol by making tumor cells more sensitive to the drug.NCT00054522·Buffalo, New York and 1 other

CompletedA Study of JNJ-80038114 in Participants With Advanced Stage Prostate CancerThe purpose of this study is to determine recommended phase 2 dose(s) (RP2Ds) of JNJ-80038114 in Part 1 (dose escalation) and to determine the safety at the RP2D(s) in Part 2…NCT05441501·Minneapolis, Minnesota and 5 others

Active not recruitingTalazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPCThis study compares rPFS in men with mCRPC treated with talazoparib plus enzalutamide vs. enzalutamide after confirmation of the starting dose of talazoparib in combination with…NCT03395197·Anchorage, Alaska and 369 others

CompletedA Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate CancerThe purpose of this study is to assess the safety and effectiveness of nivolumab with docetaxel in men with advanced castration resistant prostate cancer who have progressed after…NCT04100018·Mobile, Alabama and 292 others

CompletedEfficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)This study will assess the efficacy and safety of pembrolizumab plus enzalutamide plus Androgen Deprivation Therapy (ADT) versus placebo plus enzalutamide plus ADT in participants…NCT04191096·Anchorage, Alaska and 233 others

TerminatedEnzalutamide With Ribociclib in Treating Patients With Metastatic Castrate-Resistant, Chemotherapy Naive Prostate Cancer That Retains Retinoblastoma ExpressionThis phase Ib/II trial studies the safety, side effects, best dose, and effectiveness of ribociclib when given with enzalutamide in treating patients with castrate-resistant…NCT02555189·Ann Arbor, Michigan and 3 others

TerminatedNUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid TumorsNUV-868-01 is a first-in human, open- label, Phase 1/2 dose escalation and expansion study in patients with advanced solid tumors.NCT05252390·Tucson, Arizona and 21 others

CompletedA Study of Enzalutamide and LY3023414 in Men With Prostate CancerThe main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in men with prostate cancer.NCT02407054·Homewood, Alabama and 35 others

TerminatedA Study of CART-PSMA-TGFβRDN in Patients With Metastatic Castration Resistant Prostate CancerMulti-center, open-label, Phase 1 study of the safety, tolerability and feasibility of dosing patients harboring metastatic castration resistant prostate cancer (mCRPC) with…NCT04227275·Tampa, Florida and 8 others

RecruitingThis Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.This study will explore whether a combination of the investigational drug mevrometostat (PF-06821497) and enzalutamide will work better than taking enzalutamide alone in…NCT07028853·Huntsville, Alabama and 306 others

CompletedA Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid TumorsThis will be a Phase 1, open label, 2-sequence, crossover study to establish the BE of the current commercial formulation (Generation 3.1 talazoparib capsules) to the proposed…NCT04672460·Encinitas, California and 30 others

CompletedBicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate CancerThis phase II trial studies how well giving bicalutamide with or without Akt inhibitor MK2206 works in treating patients with previously treated prostate cancer.NCT01251861·Palo Alto, California and 197 others

CompletedReal-World Study of Enzalutamide and Abiraterone Acetate (With Prednisone) TolerabilityThe purpose of this study is to characterize the tolerability profiles of enzalutamide and abiraterone acetate (with prednisone) -with specific focus on central nervous system…NCT02663193·Homewood, Alabama and 19 others

CompletedA Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate CancerThe purpose of this study was to determine the efficacy and safety of oral enzalutamide compared to bicalutamide in castrate men with metastatic prostate cancer who have…NCT01288911·Homewood, Alabama and 87 others

Active not recruitingA Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical ProstatectomyThe purpose of this study is to determine if treatment with apalutamide plus androgen deprivation therapy (ADT) before and after radical prostatectomy (RP) with pelvic lymph node…NCT03767244·La Jolla, California and 202 others

CompletedInterstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate CancerRATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells.NCT00063882·Phoenix, Arizona and 169 others

WithdrawnAbemaciclib With or Without Atezolizumab in Metastatic Castration Resistant Prostate CancerThis research is studying two experimental drugs, abemaciclib and atezolizumab, alone and in combination with each other, to learn about the safety and effectiveness of these…NCT04272645·Boston, Massachusetts and 3 others

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