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Clareo Health | Pancreatic Cancer Clinical Trials in Nashville | 290 Studies

Clinical Trials Pancreatic CancerNashville

Pancreatic Cancer Clinical Trials in Nashville

Find 290 clinical trials for pancreatic cancer near Nashville, Tennessee. Connect with research centers in your area.

All Pancreatic Cancer trials nationwide All trials in Nashville

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 290 trials

TerminatedA Phase I/II Study of Lenalidomide in Combination With Gemcitabine in Patients With Untreated Advanced Carcinoma of the PancreasPhase I will determine the MDT and evaluate the safety profile of oral lenalidomide days 1-21 and weekly gemcitabine days 1, 8, \& 15 in 28 day cycles Phase II will explore the…NCT00179751·Metairie, Louisiana and 5 others RecruitingA Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic AlterationsThis phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread from where it first started to nearby tissue…NCT06906562·Birmingham, Alabama and 108 others

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Data from ClinicalTrials.govTerms

RecruitingStudy of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA TherapyThis study aims to determine the safety, pharmacokinetics (PK) and recommended Phase 3 dose (RP3D) of RYZ101 in Part 1, and the safety, efficacy, and PK of RYZ101 compared with…NCT05477576·Phoenix, Arizona and 53 others

CompletedSelumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With ChemotherapyThis randomized phase II trial studies how well selumetinib and Akt inhibitor MK2206 work compared to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) therapy…NCT01658943·Tucson, Arizona and 533 others

Active not recruitingDose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor) monotherapy in adult…NCT05462717·Springdale, Arkansas and 63 others

CompletedXB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic CancerThis trial will include 2 portions (phase 1 and phase 2).NCT04825288·Tucson, Arizona and 29 others

CompletedPaclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine Hydrochloride With or Without WEE1 Inhibitor AZD1775 in Treating Patients With Previously Untreated Pancreatic Cancer That Is Metastatic or Cannot Be Removed by SurgeryThis partially randomized phase I/II trial studies the side effects and best dose of WEE1 inhibitor AZD1775 when given together with paclitaxel albumin-stabilized nanoparticle…NCT02194829·Chicago, Illinois and 4 others

CompletedA Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid TumorsThe main purpose of this study is to evaluate the safety and tolerability of anti-programmed cell death ligand 1 (PD-L1) checkpoint antibody LY3300054 in participants with…NCT02791334·Nashville, Tennessee and 13 others

RecruitingA Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionThe goal of this study is to test autologous logic-gated Tmod™ CAR T-cell products in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC)…NCT06051695·Gilbert, Arizona and 11 others

UnknownA Study to Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA MutationsThis is a phase 1, Open-label, multicenter Dose Escalation study of BTP-114, a novel platinum product, in patients with advanced solid tumors and BRCA or other DNA repair mutation.NCT02950064·Sarasota, Florida and 7 others

CompletedSafety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer SettingTest the safety, immune response and efficacy of GVAX pancreas vaccine (with cyclophosphamide) and CRS-207 compared to chemotherapy or CRS-207 alone in adults with previously…NCT02004262·Scottsdale, Arizona and 20 others

TerminatedA Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)This is a study in participants with Exocrine Pancreatic Insufficiency (EPI) due to pancreatic cancer.NCT03859869·Birmingham, Alabama and 32 others

CompletedA Study of Galunisertib (LY2157299) and Durvalumab (MEDI4736) in Participants With Metastatic Pancreatic CancerThe main purpose of this study is to evaluate the safety and efficacy of the study drug known as galunisertib administered in combination with the anti-programmed cell…NCT02734160·Scottsdale, Arizona and 10 others

CompletedStudy to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple MyelomaThe main purpose of this first human study with CC-223 is to assess the safety and action of a new class of experimental drug (dual mTOR inhibitors) in patients with advanced…NCT01177397·Los Angeles, California and 15 others

CompletedGemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00026338·Tucson, Arizona and 172 others

CompletedA Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine TreatmentThe purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for cancer therapy, namely 5…NCT04083235·Birmingham, Alabama and 199 others

CompletedEffects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid TumorsThis is a Phase I study to test the safety, pharmacokinetics and effectiveness of STM 434 alone, or in combination with liposomal doxorubicin, in patients with ovarian cancer or…NCT02262455·Boston, Massachusetts and 3 others

TerminatedStudy of Ruxolitinib in Pancreatic Cancer Patients (Janus 1)Determining the efficacy, based upon overall survival, of ruxolitinib added to capecitabine for the treatment of advanced or metastatic pancreatic cancer.NCT02117479·Avondale, Arizona and 229 others

CompletedGemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary CancerRATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or…NCT00987766·Nashville, Tennessee

CompletedA Study of the GSK MEK Inhibitor GSK1120212 and Everolimus in Cancer SubjectsThe purpose of this study is to determine the recommended dose and regimen for the orally administered MEK inhibitor GSK1120212 dosed in combination with everolimus in subjects…NCT00955773·Nashville, Tennessee and 2 others

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