Ovarian Cancer Clinical Trials

Showing 301-320 of 902 trials

A Study of XS-02 Capsules in Patients With Advanced Solid Tumors

NCT06531486

A study to evaluate the safety, tolerability, Pharmacokinetics(pk), and efficacy of XS-02 capsules in patients with advanced solid tumors.

Solid TumorOvarian CancerBreast Cancer+1 more

NovaOnco Therapeutics Co., Ltd.96 participantsStarted Jul 2024

TERMINATEDPhase 1/2

A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

NCT04408599

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

Advanced or Metastatic Solid TumorsOvarian CancerGastric Cancer+1 more

NextCure, Inc.46 participantsStarted Jun 2020

Bethesda, Maryland, United States • Hackensack, New Jersey, United States • New York, New York, United States +2 more locations

COMPLETEDPhase 1

First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b

NCT06517433

First-in-human, Phase 1b/2 safety study of the antibody-drug conjugate (ADC) XMT-1536 (upifitamab rilsodotin) administered as an intravenous infusion once every four weeks. Patients with tumor types likely to express NaPi2b were enrolled in dose escalation. Patients with platinum-resistant ovarian cancer and non-small cell lung cancer (adenocarcinoma subtype) were enrolled in the expansion segment of this study. In addition to safety assessments, the pharmacokinetics of the drug were assessed along with ADC activity.

Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic

Mersana Therapeutics62 participantsStarted Dec 2017

Oklahoma City, Oklahoma, United States

A Study of XS-02 Capsules in Patients With Advanced Solid Tumors

A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b

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Plasmodium Immunotherapy for Advanced Ovarian Cancer

HRD Status Reference Standard Based on WGS

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Study of ADCT-301 in Patients With Selected Advanced Solid Tumors

Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod

Japan Phase 2 Study of Niraparib (Maintenance Therapy) in Participants With Relapsed Ovarian Cancer

Adebrelimab Plus Chemotherapy, Bevacizumab and Fluzoparib in Platinum-Sensitive Relapsed Ovarian Cancer

Early Detection of Relapse in Ovarian Cancer Using Capillary Home-sampling and a Protein Biomarker Test

Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab

4FMFES-PET Imaging of Endometrial and Ovarian Cancers

LCC-CARIS-01: Molecular Profiling in Gynaecological Cancer

Efbemalenograstim Alfa Injection for Ovarian or Cervical Cancer Receiving Chemotherapy Regimen

Fasting Mimicking Diet (FMD) in Conjunction With Chemotherapy in Advanced Ovarian Cancer

(GI-RADS) in Preoperative Evaluation of Adnexal Masses

A Study of DeTIL-0255 in Adults With Advanced Malignancies

Patient Reported Outcomes Study Using Electronic Monitoring System for Advanced or Metastatic Solid Cancer

The Efficacy of WeChat-based Multidisciplinary Full-course Nutritional Management Program