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Clareo Health | Ovarian Cancer Clinical Trials in Pennsylvania | 530 Studies

Clinical Trials Ovarian CancerPennsylvania

Ovarian Cancer Clinical Trials in Pennsylvania

Find 530 clinical trials for ovarian cancer near Pennsylvania. Connect with research centers in your area.

All Ovarian Cancer trials nationwide All trials in Pennsylvania

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 481-500 of 530 trials

CompletedPhase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine CytoprotectRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003425·Lexington, Kentucky and 3 others RecruitingA Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or UbamatamabThis study is researching an investigational drug called REGN5668 : * alone or, * combined with cemiplimab (also known as REGN2810) or, * combined with both cemiplimab and…NCT04590326·Duarte, California and 27 others

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Data from ClinicalTrials.govTerms

CompletedEnzastaurin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal CancerRATIONALE: Enzastaurin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.NCT00407758·Los Angeles, California and 15 others

TerminatedMOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal CancerPhase I study to establish safety and feasibility of intraperitoneally administered lentiviral transduced MOv19-BBz CAR T cells with or without cyclophosphamide + fludarabine as…NCT03585764·Philadelphia, Pennsylvania

TerminatedPaclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV InfectionThis phase I clinical trial is studying the side effects and the best dose of vorinostat when given together with paclitaxel and carboplatin in treating patients with metastatic…NCT01249443·La Jolla, California and 9 others

RecruitingA Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably.NCT06890338·Birmingham, Alabama and 69 others

Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

Active not recruitingA Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary MalignanciesThis is a Phase 2, multicenter, two-stage, open-label, parallel-group study designed to evaluate the efficacy and safety of vudalimab (XmAb20717) in patients with selected…NCT05032040·Prescott, Arizona and 16 others

Active not recruitingTesting the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVThis phase I trial investigates the side effects of cabozantinib and nivolumab in treating patients with cancer that may have spread from where it first started to nearby tissue…NCT04514484·Chicago, Illinois and 2 others

CompletedInterleukin-12 in Treating Patients With Refractory Advanced-Stage Ovarian Cancer or Abdominal CancerPhase I trial to study the effectiveness of interleukin-12 in treating patients with refractory ovarian or abdominal cancers.NCT00003439·Pittsburgh, Pennsylvania

TerminatedA Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid TumorsThis research study is studying a new drug, NC762, as a possible treatment for advanced or metastatic solid tumors.NCT04875806·New Haven, Connecticut and 7 others

TerminatedA Comparative Pharmacokinetics and Safety Study of OvaRex MAb-B43.13 in Patients With Ovarian Epithelial CarcinomaThe study will compare the pharmacokinetic profile of OvaRex MAb-B43.13 ascites fluid product and OvaRex MAb-B43.13 cell culture product.NCT00034138·Miami, Florida and 7 others

TerminatedREFRaME-O1: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator's Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1A Phase 2/3 study to investigate the efficacy and safety of luveltamab tazevibulin versus IC chemotherapy in women with ovarian cancer (including fallopian tube or primary…NCT05870748·Tucson, Arizona and 62 others

TerminatedDelayed Initiation of Olaparib Maintenance Therapy in Platinum Sensitive Recurrent Ovarian CancerThe purpose of this study is to test if delaying the start of the olaparib until there is a rise in a tumor marker called CA-125 will result in a longer time until the next or…NCT04377087·Pittsburgh, Pennsylvania

TerminatedNM32-2668 in Adult Patients With Selected Advanced Solid TumorsThis is a first-in-human, open-label, multi-center, Phase 1, dose-escalation study with expansion cohorts to evaluate NM32-2668 for safety and immunogenicity, to determine the…NCT06299163·Birmingham, Alabama and 10 others

CompletedOlaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor StatusThis is a non-randomized, open-label study to assess olaparib tablets as a treatment for subjects with different homologous recombination deficiency (HRD) tumor status and with…NCT02983799·Anchorage, Alaska and 46 others

RecruitingSapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial CancerThis is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of sapanisertib and serabelisib (PIKTOR) with paclitaxel in participants with…NCT06463028·La Jolla, California and 17 others

TerminatedYKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer Receiving ChemotherapyThis research trial studies chitinase 3-like 1 (cartilage glycoprotein-39) (YKL-40) in serum samples from patients with newly diagnosed stage III-IV ovarian epithelial, primary…NCT00899093·Mobile, Alabama and 130 others

CompletedA Study to Evaluate the Safety and Antitumor Activity in Subjects With Advanced Solid TumorsTo determine the maximum tolerated dose or optimal biological dose, and the safety profile of MEDI3617 when given as a single-agent or in combination with other chemotherapeutic…NCT01248949·Los Angeles, California and 9 others

RecruitingA Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian CancersThis study is researching an experimental CAR T cell therapy called 27T51, referred to as study drug.NCT06469281·Boston, Massachusetts and 4 others

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Other Conditions in Pennsylvania

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