Obesity Clinical Trials

Showing 1581-1600 of 4,967 trials

Deep Phenotyping of Peripheral Blood Cells and Circulating Factors in Metabolic Diseases

NCT06396871

The goal of this cross-sectional observational study is to to perform a thorough characterization of the quantitative and qualitative differences in peripheral blood cells, and circulating factors (proteins, metabolites, lipids, extracellular vesicles) in different stages of several metabolic diseases (diabetes, obesity, non-alcoholic fatty liver disease) that share common pathophysiological mechanisms and in comparison with adult healthy controls. The main question\[s\] it aims to answer are: * Which are the quantitative (number and concentration) and qualtitative (characteristics, functional assays) differences in platelets in patients with metabolic diseases vs subjects without metabolic diseases * Which are the quantitative (number and concentration) and qualtitative (characteristics, functional assays) differences in leucocytes or circulating molecules in patients with metabolic diseases vs subjects without metabolic diseases

NAFLDDiabetes MellitusObesity

Technische Universität Dresden180 participantsStarted Oct 2023

Dresden, Saxony, Germany

UNKNOWNPhase 2/3

Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy

NCT05930184

The goal of this randomized controlled trial is to compare laparoscopic guided peri-wound Transversus Abdominis Plane Block and bupivacaine versus local wound infiltration effect on reducing post-op opioid use in Laparoscopic Sleeve gastrectomy. The main questions it aims to answer are: • Can laparoscopic guided peri-wound Transversus Abdominis Plane Block reduced post operative morphine usage when comparing with local wound port site infiltration. Participants will be randomize into 2 group * peri-wound Transversus Abdominis Plane Block * local wound port site infiltration

Morbid ObesityLaparoscopic Sleeve GastrectomyTransversus Abdominis Plane Block+3 more

Khon Kaen University98 participantsStarted Apr 2023

Khon Kaen, Northeastern, Thailand

Deep Phenotyping of Peripheral Blood Cells and Circulating Factors in Metabolic Diseases

Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy

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