Obesity Clinical Trials

Showing 381-400 of 2,358 trials

Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

NCT04297592

To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.

Infections Joint ProstheticOverweight or ObesityMSSA Colonization+6 more

Mayo Clinic4,618 participantsStarted Jun 2020

Iowa City, Iowa, United States • Rochester, Minnesota, United States

COMPLETEDPHASE2

DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway

NCT04963231

The purpose of this study was to evaluate the safety and efficacy of once daily subcutaneous (SC) administration of setmelanotide in participants with obesity and specific gene variants in the MC4R pathway.

Genetic Obesity

Rhythm Pharmaceuticals, Inc.164 participantsStarted Nov 2021

Scottsdale, Arizona, United States • Suwanee, Georgia, United States • Worcester, Massachusetts, United States +33 more locations

Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

DAYBREAK: A Study of Setmelanotide in Participants With Specific Gene Variants in the Melanocortin-4 Receptor (MC4R) Pathway

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