Obesity Clinical Trials in Houston

Showing 101-120 of 212 trials

GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response

NCT04387201

This project investigates the anti-obesity mechanisms of glucagon-like peptide-1 (GLP-1) analogs, which are used in the treatment of human obesity and diabetes mellitus. The investigators will test if GLP-1 induces secretion of interleukin-6 (IL-6), a cytokine that may collaborate with GLP-1 analogs to induce the formation of brown fat, which has anti-diabetic properties. The results will guide future obesity and diabetes mellitus therapies.

Glucose IntoleranceOverweight and ObesityDrug Effect+1 more

The University of Texas Health Science Center, Houston23 participantsStarted May 2020

Houston, Texas, United States

COMPLETEDPhase 3< 1 mile

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

NCT04660643

This was a study of tirzepatide in participants with obesity or overweight. The main purpose was to learn more about how tirzepatide maintained body weight loss. The study had two phases: a lead-in phase in which all participants took tirzepatide and a treatment phase in which participants either continued tirzepatide or switched to placebo. The study lasted about 2 years (25 visits).

ObesityOverweight

Eli Lilly and Company783 participantsStarted Mar 2021

Pelham, Alabama, United States • La Jolla, California, United States • Los Angeles, California, United States +67 more locations

GLP-1 Therapy: The Role of IL-6 Signaling and Adipose Tissue Remodeling in Metabolic Response

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss

Obesity Trials in Other Cities

A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program

Extended Criteria For Fetal Myelomeningocele Repair

The Effect of Epitomee Capsule on Body Weight in Patients With Overweight and Obesity

The i Heart Rhythm Project: Healthy Sleep and Behavioral Rhythms for Obesity Prevention

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Promoting The Self-Regulation Of Energy Intake

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

Efficacy and Safety of ALT-801 in the Treatment of Obesity

Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity

Study to Assess Safety, Tolerability and Efficacy of SC Administered MBL949 in Obese Participants With or Without T2DM

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants

International Weight Control Registry

Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II

A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight

A Phase 1 Study of DD01 in Overweight/Obese Subjects With T2DM and NAFLD

Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial

Other Conditions in Houston