Multiple Sclerosis Clinical Trials

Showing 1541-1560 of 2,839 trials

Bone Loss Treatment From Adjuvant Zoledronate Efficacy

NCT01623908

The main purpose of this study is to observe and assess the impact of adjuvant zoledronate on bone density in breast cancer patients. The second purposes: * The efficacy of adjuvant zoledronate * The safety of adjuvant zoledronate * The bone loss of breast cancer patients in Guangdong * The correlation between bone loss of breast cancer patients and treatment of disease in Guangdong

Breast NeoplasmsBone Loss

First Affiliated Hospital, Sun Yat-Sen University200 participantsStarted Jul 2011

Dongguan, Guangdong, China • Guangzhou, Guangdong, China • Guangzhou, Guangdong, China +7 more locations

UNKNOWNNA

Contrast-enhanced Ultrasonography Combined With Blue Dye as Dual-tracer for Sentinel Lymph Node Biopsy

NCT04932460

False negative rate (FNR) in patients who has accepted neoadjuvant therapy is high. Blue dye and radioisotope as dual-tracer can decrease FNR. Several large clinical trials showed that using dual trace with blue dye and radioisotope can reduce the FNR to less than 10%. But radioisotope is still not approved in China and can cause radiocontamination. A novel dual-tracer which can decrease the FNR in patients after neoadjuvant therapy is urged to be explored. Contrast enhanced ultrasonography (CEUS) can make the lymphatic drainage path and sentinel lymph nodes visible. Retrospective studies found that CEUS can locate SLN precisely. So this clinical trial aim to evaluate FNR, detective rate and numbers of SLN by using CEUS combined with blue dye as dual-tracer in sentinel lymph node biopsy in breast cancer patients after neoadjuvant therapy and the accuracy of CEUS for the diagnosis of lymph node metastasis before and after neoadjuvant therapy.

Breast NeoplasmsNeoadjuvant TherapySentinel Lymph Node Biopsy

First Affiliated Hospital, Sun Yat-Sen University350 participantsStarted Jun 2021

Guangzhou, Guangdong, China

Bone Loss Treatment From Adjuvant Zoledronate Efficacy

Contrast-enhanced Ultrasonography Combined With Blue Dye as Dual-tracer for Sentinel Lymph Node Biopsy

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