Multiple Sclerosis Clinical Trials

Showing 1241-1260 of 5,960 trials

A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

NCT06869278

This is a prospective, single-arm, open-label, dose-exploration and expansion clinical study of LCAR-AIO in adult subjects with relapsed/refractory neurological autoimmune diseases.

Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disease (NMOSD)Anti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD)+1 more

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology37 participantsStarted Jun 2025

Fuzhou, China • Suzhou, China • Wuhan, China

RECRUITINGNA

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

NCT05051618

The purpose of this research is to examine the effects of two different exercise training regimens for managing depression and improving other health indicators among persons with multiple sclerosis (MS). The project will enroll persons with MS and major depressive disorder (MDD) between 18 and 64 years of age. The investigators will enroll a total of 146 participants. This is a Phase-II trial that compares the efficacy of an exercise training program (POWER-MS) compared with a stretching program (FLEX-MS) for immediate and sustained reductions in the severity of depression among persons with MS who have MDD.

Multiple SclerosisMajor Depressive Disorder

University of Illinois at Chicago146 participantsStarted Apr 2023

Chicago, Illinois, United States

A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

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