Multiple Sclerosis Clinical Trials

Showing 4341-4360 of 5,960 trials

DAOIB for the Treatment of Cognitive Function and Behavioral and Psychological Symptoms of Dementia

NCT02103673

The population of dementia is increasing rapidly. Cognitive impairment as well as Behavioral and psychological symptoms of dementia (BPSD) add heavy burdens to caregiver. NMDA activation is critical for learning and memory. Individuals with Alzheimer's disease (AD) have fewer NMDA receptors in the frontal cortex and hippocampus than controls. This study is a randomized, double-blind, placebo-controlled drug trial. All patients will be allocated randomly to two groups: (1) NMDA enhancer: DAOIB (starting dosage: 250-500 mg/day), (2) placebo, for 6 weeks. The investigators hypothesize that DAOIB may yield better efficacy than placebo for cognitive function and clinical symptoms in patients with BPSD.

Behavioral and Psychological Symptoms in Alzheimer's DiseaseBehavioral and Psychological Symptoms in Vascular Dementia

Chang Gung Memorial Hospital90 participantsStarted Feb 2014

Kaohsiung City, Taiwan • Taichung, Taiwan

COMPLETED

Second Primary Cancers in Patients With Castration Resistant Prostate Cancer

NCT02702908

This study aims at estimating the incidence of second primary malignancies as well as the overall survival among metastasized prostate cancer (mPC) and metastasized castrate-resistant prostate cancer (mCRPC) patients not treated with radium-223-dichloride.

Prostatic Neoplasms

Bayer6,442 participantsStarted Mar 2016

Multiple Locations, Germany

TERMINATEDPhase 4

Single Center, Open Label, Study of Preparation H on Erythema in Relapsing MS Patients Treated With PLEGRIDY

NCT02665221

The primary purpose of this single center, randomized, open label study in relapsing Multiple Sclerosis (MS) patients on PLEGRIDY (peginterferon beta-1a) is to assess the effect of Preparation H (phenylephrine) Maximum Strength Cream compared to no topical treatment of injection site erythema after PLEGRIDY injection.

Multiple Sclerosis

NYU Langone Health30 participantsStarted Jul 2015

New York, New York, United States

DAOIB for the Treatment of Cognitive Function and Behavioral and Psychological Symptoms of Dementia

Second Primary Cancers in Patients With Castration Resistant Prostate Cancer

Single Center, Open Label, Study of Preparation H on Erythema in Relapsing MS Patients Treated With PLEGRIDY

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