Multiple Sclerosis Clinical Trials

Showing 4121-4140 of 5,960 trials

A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

NCT01688206

This multi-center, open-label study will evaluate the safety, pharmacokinetics, pharmacodynamics and preliminary efficacy of vanucizumab as a single agent or in combination with atezolizumab in participants with locally advanced or metastatic solid tumors. Cohorts of participants will receive escalating doses of vanucizumab, fixed dose of vanucizumab (MTD and/or recommended phase two dose \[RP2D\]), and fixed dose of vanucizumab in combination with atezolizumab, intravenously every 2 weeks.

Neoplasms

Hoffmann-La Roche132 participantsStarted Oct 2012

Brussels, Belgium • Leuven, Belgium • Bordeaux, France +11 more locations

TERMINATEDNA

Extensive Staging in Lung Cancer

NCT02030444

The overall aim of this study is to compare standard staging of lung cancer (which includes clinical examination, CT, MRI, bone scan and PET-CT) with comprehensive staging - which includes the new staging methods (PET-MRI and systematic mapping of mediastinal and hilar lymph nodes using endobronchial ultrasound) with respect to disease stage and outcomes of therapy.

Lung Neoplasms

St. Olavs Hospital32 participantsStarted Aug 2014

Trondheim, Norway

A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Extensive Staging in Lung Cancer

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