Multiple Sclerosis Clinical Trials

Showing 321-340 of 2,839 trials

Exercise Intensity on Brain & Mental Health in Stress

NCT06245538

This study aims to examine the role of exercise intensity in the acute effects of a single bout of aerobic exercise on neurotrophic factors, biomarkers of stress and inflammation, working memory task-related changes in prefrontal cortex oxygenation in adults with sub-clinical levels of stress-related symptoms.

Healthy AdultsAdults With Stress-related Symptoms

The Swedish School of Sport and Health Sciences24 participantsStarted Feb 2024

Stockholm, Sweden

ACTIVE_NOT_RECRUITINGNA

The Purpose of the Study is to Investigate if a Smartphone App Combined With Internet Based Cognitive Behavioural Therapy (ICBT) Leads to Improved Symtoms in Depressive Adults on Antidepressive Medicine, Compared to a Wait-list Control Condition

NCT06907134

The purpose of the study is to investigate if a smartphone app combined with internet delivered cognitive behavioural therapy (ICBT) leads to improved symptoms in depressive adults on antidepressive mediation. The participants in the treatment group will get access to a smartphone app based on CBT-principles for 9 weeks. They will also get access to an internet platform with extra treatment material based on CBT and receive therapist support on demand. Participants will be recruited in Sweden with nationwide recruitment.

Depressive Symptoms

Linkoeping University150 participantsStarted Nov 2024

Linköping, Östergötland County, Sweden

RECRUITINGPHASE1

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

NCT06912087

This Phase I clinical trial evaluates the safety, tolerability, and optimal dosing of Zanzalintinib in combination with Pembrolizumab and Cetuximab in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M HNSCC). The study aims to establish the maximally tolerated dose (MTD) and recommended Phase II dose (RP2D) while also exploring efficacy outcomes, including progression-free survival (PFS) and overall survival (OS).

Head and Neck NeoplasmsCarcinoma, Squamous CellNeoplasm Recurrence, Local+3 more

University of Chicago36 participantsStarted Sep 2025

Chicago, Illinois, United States

Exercise Intensity on Brain & Mental Health in Stress

The Purpose of the Study is to Investigate if a Smartphone App Combined With Internet Based Cognitive Behavioural Therapy (ICBT) Leads to Improved Symtoms in Depressive Adults on Antidepressive Medicine, Compared to a Wait-list Control Condition

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

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The Effect of Abdominal Massage Applied to Patients by Caregivers in Palliative Care Clinics on Gastrointestinal Symptoms

Olaparib & Radiation Therapy for Patients Triple Negative Breast Cancer (TNBC)

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POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)

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A Chinese Cohort of Cervical Large Cell Neuroendocrine Carcinoma

Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer

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